Synthesis of α,β-Unsaturated Amide via Phosphonium Ylide

Zinc-Mediated Facile Synthesis of α,β-Unsaturated Primary Amides

“…11 However, in many cases these methods were of limited scope. The Wittig reaction 12 is one of the most important general methods for the construction of carbon-carbon double bonds, and as a part of our studies on developing new Wittig reactions, [13][14][15][16] we considered developing a general route to α,β-unsaturated primary amide via a Wittig method.…”

Phosphonium salts and P-ylides

“…in good yields with high E-selectivity, starting from preformed carbamoylmethylenetriphenylphosphorane ylide,127 continue the long list of publications where this task-oriented reaction was used.…”