Synthesis of α-amino acid derived (1,2,3-triazol-4-yl)-picolinamide (tzpa) ligands and their corresponding luminescent Tb(iii) complexes

Abstract

The synthesis of chiral α-amino acid derived (1,2,3-triazol-4-yl)-picolinamide (tzpa) ligands 4-6 designed by combining the coordination properties of two well-known ligand structures within a single unit is described. The self-assembly...

Modified synthetic peptides: from therapeutics to chemosensors

“…This diversity is valuable for creating peptides with specific 205 with permission from Royal Society of Chemistry, copyright 2023). 205 chemical, electronic, or steric characteristics. The Gunnlaugsson group elegantly exploited this idea with their recent publication detailing the synthesis of chiral α-amino acid derived ligands for Ln 3+ luminescence.…”

“…The Gunnlaugsson group elegantly exploited this idea with their recent publication detailing the synthesis of chiral α-amino acid derived ligands for Ln 3+ luminescence. 205 These novel ligands contained l -phenylalanine and l -tryptophan – as their methyl esters – which underwent supramolecular self-assembly to form 1 : 3 complexes with Tb 3+ under thermodynamic control. Indeed, both complexes were able to evoke Tb 3+ -centred emission ( λ ex = 255 nm).…”

“…23 Structures of ligands Phe & Trp, and the delayed luminescence spectra of [Tb(Phe) 3 ] 3+ recorded in MeCN. Inset: Picture of complex solution under illumination via UV lamp (adapted from ref.205 with permission from Royal Society of Chemistry, copyright 2023) 205.…”

Two-Photon Circularly Polarized Luminescence of Chiral Eu Complexes

“…Following this strategy, enantiomer pairs of Eu 3+ complexes for both the i Pr and Ph-PyBox derivatives were synthesized (Scheme ). On one hand, PyBox ligands have shown to be suitable chirality inducers in both homo- and heteroleptic complexes. − On the other hand, Maury et al showed that the strategy of ligands with extended conjugation and strong push–pull systems with varying charge-transfer character provides high 2PE cross sections in the case of dipicolinic acid derivatives. ,,− …”

“… 36 − 43 On the other hand, Maury et al showed that the strategy of ligands with extended conjugation and strong push–pull systems with varying charge-transfer character provides high 2PE cross sections in the case of dipicolinic acid derivatives. 31 , 32 , 44 − 54 …”