Synthesis of xanthene derivatives by employing Fe3O4nanoparticles as an effective and magnetically recoverable catalyst in water

Abstract

An efficient and environmentally adapted synthesis of xanthene derivatives by condensation of a wide range of aryl aldehydes and 1,3-cyclohexanediones in water using a catalytic amount of Fe 3 O 4 nanoparticles is explained. The Fe 3 O 4 nanoparticles were characterized by powder X-ray diffraction (XRD), transmission electron microscopy (TEM) and FT-IR spectroscopy.

Novel Tri- and Tetra-substituted Pyrimido[4,5-d]pyridazines: Regiospecific Synthesis Catalyzed by Silica Supported Yttrium Trinitrate

“…[9][10][11] In this direction, some workers synthesized a number of heterocyclic compounds, but, to the best of our knowledge, no reaction of 5-acetyl-4-aryloyl-6-methyl-3,4-dihydropyrimidinones with hydrazine derivatives has been previously reported. In view of the above observations and as a continuation of our ongoing programs directed to the synthesis of heterocyclic compounds [12][13][14] and catalyzed organic reactions, [15][16][17] we report herein, the synthesis of some new tri-and tetra-substituted pyrimido [4,5-d]pyridazines-2(1H,3H,7H)-ones 3 by using 5-acetyl-4-aryloyl-6-methyl-3,4-dihydropyrimidinones 1 and various hydrazines 2 as starting materials in the presence of immobilized yttrium trinitrate on silica gel as a safe and recyclable catalyst under solvent-free conditions (Scheme 1).…”

ZnO Nanoparticles – a Recyclable Catalyst for the Synthesis of Bis(Pyrazolyl)Methanes

“…In recent studies, some research groups have focused on a catalyst-promoted synthesis of bis(pyrazolyl)methanes where an aromatic aldehyde is condensed with 5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one under various conditions [8][9][10][11][12][13][14][15][16][17]. Despite several advantages, some of the reported methods suffer from disadvantages such as long reaction times, low product yield, and use of extra tools and unrecyclable catalysts.According to the green chemistry principles, the use of recyclable catalysts and replacement of toxic organic solvents by safe and clean ones are effective ways to prevent waste production in chemical reactions [18][19][20]. Nanocatalysis has recently attracted much attention from chemists because of its notable features.…”

The first practical approach to new pyrimido[4,5-d]pyridazines: novel chemoselective and regioselective reactions

“…Not only the ecological profile (through helping to decrease hazardous industrial waste), but also the economic profile (through the elimination of expensive organic solvent) is further improved if the catalyst be recyclable and reaction conditions be solvent-free. [19][20][21] It should be noted that our efforts for the present reactions without using catalyst were unsuccessful. In general, TSA has valuable and special features including: a) reaction carried out under solvent free conditions; b) high thermal stability; c) a small amount of recyclable catalyst used making this reaction economic and eco-friendly.…”