Synthesis of water-soluble chitosan from squid pens waste as raw material for capsule shell: temperature deacetylation and reaction time

Yusharani, Malinda Syifa; Stenley,; Harmami,; Ulfin, Ita; Ni’mah, Yatim Lailun

doi:10.1088/1757-899x/509/1/012070

Cited by 17 publications

(6 citation statements)

References 26 publications

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“…Therefore, water-soluble chitosan (WSC)—a modification of chitosan with higher solubility in neutral pH solution—also attracts great attention from many researchers. WSC can be obtained from chitosan in different ways, including shortening chitosan chains, increasing the degree of deacetylation or introducing hydrophilic groups into chitosan molecules So far, WSC demonstrates numerous activities, such as anti-cancer, anti-oxidant, or anti-microbial [11,12,13,14].…”

Section: Introductionmentioning

confidence: 99%

Anti-Oxidant and Anti-Diabetes Potential of Water-Soluble Chitosan–Glucose Derivatives Produced by Maillard Reaction

et al. 2019

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Chitosan-sugar derivatives demonstrate some useful biology activities (for example anti-oxidant and anti-microbial activities). In this study, water-soluble chitosan–glucose derivatives (WSCGDs) were produced from a water-soluble chitosan hydrochloride (WSC) with 12.5 kDa of molecular weight and 24.05% of degree of acetylation (DA) via Maillard reaction with the heating temperatures of 100 °C and 121 °C. The Maillard reaction between WSC and glucose was investigated by measuring the absorbances at 420 nm and 294 nm, indicating that the reaction took place more effectively at 121 °C. All WSCGDs exhibited higher anti-oxidant activity than WSC, in which WSCGDs obtained at the treatment 121 °C for 2 h, 3 h, and 4 h expressed the highest ability (IC50 range from 1.90–1.05 mg/mL). Increased anti-α-amylase and anti-α-glucosidase activities were also observed in WSCGDs from the treatment at 121 °C. In detail, the highest IC50 values of anti-α-amylase activity were 18.02 mg/mL (121 °C, 3 h) and 18.37 mg/mL (121 °C, 4 h), whereas the highest IC50 values of anti-α-glucosidase activity were in range of 7.09–5.72 mg/mL (121 °C, for 1–4 h). According to the results, WSCGD obtained from 121 °C for 3 h was selected for further characterizing by high performance liquid chromatography size exclusion chromatography (HPLC SEC), colloid titration, FTIR, as well as 1H-NMR, indicating that the derivative of WSC and glucose was successfully synthesized with a molecular weight of 15.1 kDa and degree of substitution (DS) of 34.62 ± 2.78%. By expressing the excellent anti-oxidant and anti-diabetes activities, WSCGDs may have potential use in health food or medicine applications.

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Section: Introductionmentioning

confidence: 99%

Anti-Oxidant and Anti-Diabetes Potential of Water-Soluble Chitosan–Glucose Derivatives Produced by Maillard Reaction

et al. 2019

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“…During the deacetylation of the chitin C-2 position, the acetamide group is converted into amino groups (-NH 2 ) [17]. When the percentage of amino groups attains around 50% or more, the polymer becomes soluble in aqueous acidic media, and in this case, chitosan can be obtained [18]. Alkaline hydrolysis with sodium hydroxide (40-50%) at high temperatures (80-120 °С) is the most common method for extracting chitosan from chitin [19].…”

mentioning

confidence: 99%

Chitosan based-nanoparticles and nanocapsules: Overview, physicochemical features, applications of a nanofibrous scaffold, and bioprinting

Shoueir

El-Desouky

Rashad

et al. 2021

International Journal of Biological Macromolecules

118

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“…aeruginosa, E. coli (Al-Zahrani, 2021). Using as raw material chitin extracted from squid, Yusharani et al (2019) have obtained chitosan with a degree of deacetylation of 82-84%. With chitosan with a high degree of deacetylation, obtained from squid chitin, Cuong et al (2022) have formulated chitosan-tripolyphosphate nanomaterials, using chitosan, TPP, and acetic acid as raw materials.…”

Section: Introductionmentioning

confidence: 99%

Antimicrobial Properties of the Bioproducts Formulated with Chitosan and Collagen

Mohammed¹,

Radu²,

Schröder³

et al. 2022

Proceedings of the 9th International Conference on Advanced Materials and Systems

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Three types of formulations (stable suspensions) based on collagen, chitosan, limonene and an imidazole derivative were studied through in vitro tests, from the point of view of antimicrobial activity. The results obtained on 4 standardized microorganisms, namely Pseudomonas aeruginosa, Escherichia coli, Staphylococcus aureus, Staphylococcus aureus MRSA, Candida albicans, demonstrated that most of the obtained bioproducts have a local effect (inhibition diameters below 15 mm are obtained) and moderate effect (inhibition diameters located under 20 mm), except bioproducts containing collagen, chitosan, limonene and an imidazole derivative (antibiotic reagent) in mass ratio Col:Chit:Lim:CT=1:1:1:0.1, Col:Chit:Lim:CT=1:1:0:0.1 which exhibit a significant antimicrobial effect on Staphylococcus aureus and Staphylococcus aureus MRSA. These two formulations also exhibit significant antimicrobial effects for Candida albicans, for which the average inhibition diameters obtained are greater than 34 mm.

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Synthesis of water-soluble chitosan from squid pens waste as raw material for capsule shell: temperature deacetylation and reaction time

Cited by 17 publications

References 26 publications

Anti-Oxidant and Anti-Diabetes Potential of Water-Soluble Chitosan–Glucose Derivatives Produced by Maillard Reaction

Anti-Oxidant and Anti-Diabetes Potential of Water-Soluble Chitosan–Glucose Derivatives Produced by Maillard Reaction

Chitosan based-nanoparticles and nanocapsules: Overview, physicochemical features, applications of a nanofibrous scaffold, and bioprinting

Antimicrobial Properties of the Bioproducts Formulated with Chitosan and Collagen

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