Synthesis of water soluble chitosan derivatives with halogeno-1,2,3-triazole and their antifungal activity

Li, Qing; Tan, Wenqiang; Zhang, Caili; Gu, Guodong; Guo, Zhanyong

doi:10.1016/j.ijbiomac.2016.06.006

Cited by 60 publications

(44 citation statements)

References 38 publications

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“…Hydrophobic 6‐amino‐lactose (product C) was synthesized as follow : Ph 3 P (10 mmol) and B (5 mmol) were dissolved in 200 mL of anhydrous acetone and stirred for 24 h at room temperature under nitrogen atmosphere. Thereafter 1 mL of water was added and the solution was stirred for another 24 h. The solvent was removed by reduced pressure distillation.…”

Section: Methodsmentioning

confidence: 99%

Synthesis of Novel Amino Lactose and Evaluation of Its Antioxidant Property

Feng

et al. 2018

Starch Stärke

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In order to improve the bioactivity of lactose, a novel lactose derivative is designed and synthesized by introducing an amino group to the C‐6 of lactose. The in vitro antioxidant activities of synthesized lactose derivatives are assessed. It shows better scavenging activity against hydrogen peroxide (IC50 < 0.1 mg mL−1), hydroxyl radicals (IC50 0.55 mg mL−1), and DPPH radicals (IC50 0.37 mg mL−1) than lactose. Based on this data, it is reasonable to propose that the introduction of amino group through chemical modification is significant to enhance the free antioxidant activity of lactose. This derivatization strategy might provide an effective tool to broaden utilization of lactose.

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Section: Methodsmentioning

confidence: 99%

Synthesis of Novel Amino Lactose and Evaluation of Its Antioxidant Property

Feng

et al. 2018

Starch Stärke

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“…The elemental analyses were used to quantitatively assess the extent of functionalization (degree of substitution) in starch derivatives. The analyses of elemental C, N, and H in starch derivatives were performed on a Vario EL III and calculated using methods by previously report .…”

Section: Methodsmentioning

confidence: 99%

Synthesis of aminopyridinium‐grafted starch derivatives and evaluation of their antioxidant property

et al. 2017

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In order to improve the bioactivity of starch, novel starch derivatives were developed including 2-(2-aminopyridinium)acetyl starch (2APASC), 2-(3-aminopyridinium)acetyl starch (3APASC), 2-(4-aminopyridinium)acetyl starch (4APASC), 2-(2,3-diaminopyridinium)acetyl starch (2,3DAPASC), 2-(2,6-diaminopyridinium)acetyl starch (2,6DAPASC), and 2-(3,4-diaminopyridinium)acetyl starch (3,4DAPASC). The in vitro antioxidant capacities against hydroxyl-radical, DPPH-radical, and superoxide-radical for all synthesized starch derivatives were evaluated using free radicals scavenging assays. The results showed that the scavenging effect of starch derivatives bearing aminopyridinium groups was better than starch. Especially, 2,3DAPASC and 2,6DAPASC could scavenge hydroxyl-radicals completely at 0.4 mg/mL. Moreover, the antioxidant property of synthesized starch derivatives was affected by the different positions and the number of amino groups on pyridinium rings. Because the aminopyridinium acetyl starch derivatives could be synthesized conveniently and also possessed significantly strong antioxidant activity, this synthetic strategy might provide an effective tool to broaden further utilization of starch.

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“…The analyses of elemental carbon, hydrogen, and nitrogen in starch derivatives were performed on a Vario EL III (Elementar, Germany). The degrees of substitution (DS) of starch derivatives were calculated on the basis of the percentages of carbon and nitrogen according to the following equations (Dos Santos, Caroni, Pereira, da Silva, & Fonseca, 2009;Li, Tan, Zhang, Gu, & Guo, 2016).…”

Section: Elemental Analysismentioning

confidence: 99%