Synthesis of vinyl-substituted alcohols using acetylene as a C2 building block

Abstract

Vinyl-substituted alcohols represent a highly useful class of molecular skeleton. Current method typically requires either stoichiometric metallic reagents or preformed precursors. Herein, we report a nickel catalysis-enabled synthesis of vinyl-substituted...

Development of MOF-5-like ultra-microporous metal-squarate frameworks for efficient acetylene storage and separation

“…In particular, SNNU-505-Zn can uptake 60 cm 3 g −1 of C 2 H 2 at 298 K and 0.25 atm (190 mmHg), as shown in Fig. 3f, a higher capacity than many MOF absorbents, such as SNNU-150-Al, 23 HIAM-210, 24 and NUM-14. 25 When the pressure is 1 atm, SNNU-505-Zn can uptake 67.5 cm 3 g −1 of C 2 H 2 at 298 K. The relative value for SNNU-505-Co is 52.7 cm 3 g −1 and that for SNNU-505-Ni is 63.4 cm 3 g −1 .…”

Photoredox/Nickel Dual Catalysis-Enabled Modular Synthesis of Arylallyl Alcohols with Acetylene as the Two-Carbon Synthon

“…Molecular glue is a powerful strategy, which assembles the target molecules in a modular way . Small molecules, such as acetylene and ethylene, often serve as the carbon glue (Scheme C, top). Arylallyl alcohols can be regarded as two components linked with a carbon–carbon double bond.…”

Gold(I)-Catalyzed Intermolecular Aryloxyvinylation with Acetylene Gas

“…The importance of acetylene-based chemistry is best illustrated by its remarkable production market that reached 1.9 million tones in 2020 and is expected to continue growing until 2030 . Despite this, so far, chemical applications of acetylene have been mainly limited to noncatalyzed vinylation reactions or hydrochlorination processes, whereas its use in catalytic reactions has been less explored. ,− …”

“… 2 Despite this, so far, chemical applications of acetylene have been mainly limited to noncatalyzed vinylation reactions 4 or hydrochlorination processes, 5 whereas its use in catalytic reactions has been less explored. 2 , 6 − 8…”