Abstract:Abstract. Thymosin β 4Xen , a 43 residue peptide recently isolated from Xenopus laevis, was synthesized by automatic solid phase procedure and compared with the natural product, isolated from the ovaries of Xenopus laevis. For the synthesis N-methylpyrrolidone was chosen as solvent instead of the commonly used dimethylformamide because this solvent seems to be superior for solid phase peptide synthesis due to the favorable swelling properties of the polystyrene resin in this solvent and its dissolving power ag… Show more
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