Synthesis of Three Jasmin Constituents via a Central Intermediate

Abstract

Syntheses of jasmone (1), methyl jasmonate (3) and γ‐jasmolactone (2) are reported, (Z)‐nona‐1, 6‐dien‐3‐one (4) serving as common intermediate.

A Two Steps Synthesis of γ-Substituted and γ,γ-Disubstituted α-(Alkylmethylene)-γ-butyrolactones

“…γ-Butyrolactones are an important class of compounds, because they may be easily transformed into butenolides, furans, cyclopentenones, etc . The lactone moiety is also present in many natural products, expecially insect pheromones, antifungal substances, and flavor components or occurs in the essential oils of plants …”

“…1 The lactone moiety is also present in many natural products, 2 expecially insect pheromones, 3 antifungal substances, and flavor components or occurs in the essential oils of plants. 4 Recently there has been an increasingly large amount of research devoted to develop synthetic routes to polysubstituted γ-butyrolactones, in particular of R-methyleneγ-butyrolactones. 5 This has been due in large part to the interest in several biologically active natural products, which have the R-methylenelactone moiety as a major structural feature.…”