Synthesis of tetrazol-5-ylethyl derivatives of dipterocarpol

Synthesis of new A-conjugated Quinolone and Spiroindole Dammaranes by the Ozonolysis of 2,3-Indolodipterocarpol

“…Dipterocarpol [(20S)-20-hydroxydammar-24-en-3-one] is the major metabolite of oleoresins of trees Dipterocarpus species [2]. Such chemical transformations of dipterocarpol as preparation of Nvinylpyrrolidone, γ-lactone, alkoxytetrahydrofuran, hydroxy-, epoxy-, oximino-,1,2,4-trioxolane,heterocyclic, 2-cyanoethoxy-, tetrazole as well as hybrid triterpenoid-steroid and derivatives were described [3][4][5][6][7][8][9]. It was demonstrated that dammarane triterpenoids possess anticancer [10], antiviral [11][12][13], immunostimulating [14] and anti-inflammatory [15] activities.…”