Synthesis of Tetrahydroberberine N,N-Derived O-Acetamides
Ivan Vasil’evich Nechepurenko,
Nina Ivanovna Komarova,
Nariman Faridovich Salakhutdinov
Abstract:The reaction of berberine derivatives containing at the O-9 position N,N-disubstituted acetamide fragments with sodium borohydride in methanol at 0 °C leads to a mild reduction of the “C” cycle with the formation of corresponding tetrahydroberberine derivatives with moderate to good yields.
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