Synthesis of Strongly Fluorescent Molybdenum Disulfide Nanosheets for Cell-Targeted Labeling

Abstract

MoS2 nanosheets with polydispersity of the lateral dimensions from natural mineral molybdenite have been prepared in the emulsions microenvironment built by the water/surfactant/CO2 system. The size, thickness, and atomic structure are characterized by transmission electron microscopy (TEM), atomic force microscopy (AFM), and laser-scattering particle size analysis. Meanwhile, by the analysis of photoluminescence spectroscopy and microscope, the MoS2 nanosheets with smaller lateral dimensions exhibit extraordinary photoluminescence properties different from those with relatively larger lateral dimensions. The discovery of the excitation dependent photoluminescence for MoS2 nanosheets makes them potentially of interests for the applications in optoelectronics and biology. Moreover, we demonstrate that the fabricated MoS2 nanosheets can be a nontoxic fluorescent label for cell-targeted labeling application.

Colloidal synthesis of MoS2 quantum dots: size-dependent tunable photoluminescence and bioimaging

“…14,[30][31][32] The PL properties of the prepared MoS 2 QDs investigated at different excitation wavelengths are presented in Fig. 4.…”

“…33 As reported in the literature, the luminescence properties of MoS 2 QDs depend on their particle size, which is similar as the quantum size effect of semiconductor QDs. 14,15 This means that the aim to control the PL of MoS 2 QDs could be realized by adjusting their size. In colloidal solution, some experiment conditions, including reaction temperature and time, the amount of ligands, would influence the size of nanomaterials.…”

“…13 This transition results in the giant enhancement of its photoluminescence (PL) efficiency in MoS2 monolayers, which receives tremendous attention for many applications in optoelectronic and biological fields. 14,15 However, bulk MoS2 is an indirect bandgap material which shows excellent chemical and thermal stability, the difficulties remain in preparation of photoluminescent MoS2 nanomaterials. To date, some efforts have been made to achieve the synthesis of photoluminescent MoS2 materials and the existing approaches can be divided into three ways including exfoliation, substrate growth, and colloidal synthesis.…”

Two-dimensional non-carbonaceous materials-enabled efficient photothermal cancer therapy

“…Recent results have demonstrated that certain members of TMDCs were featured with low cytotoxicity, high hemo/histocompatibility and high photothermal-conversion efficiency [75][76][77][78][79][80][81]. Especially, their high biocompatibility and biosafety guarantee their potential applications in biological-and biomedicine-related fields [82][83][84][85][86][87][88][89][90][91][92][93]. In Representative scheme of in vivo PTT tumor ablation assisted by 2D nanosheets and the balance between the biosafety and PTT efficiency.…”

A layer-by-layer assembled MoS2 thin film as an efficient platform for laser desorption/ionization mass spectrometry analysis of small molecules

“…MoS 2 , a two-dimensionally layered transition metal dichalcogenides, has been widely employed in material science because of its excellent physicochemical properties, with applications in opto-electronics, 19 catalysis, 20 energy storage, 21 biosensing, 22 fluorescence imaging 23 and photothermal therapeutic applications. 24 The photothermal conversion properties of MoS 2 directly correspond to one of the requirements of a matrix for the LDI-MS analysis of small molecules.…”