Synthesis of Stable σ-Adducts by Arylation of Quinazoline

Azev, Yu. A.; Koptyaeva, O. S.; Селиверстова, Е. А.; Ivoilova, A. V.; Поспелова, T. А.

doi:10.1134/s1070363219120089

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2020

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“…It is also known that unsubstituted quinazoline reacts with indole, 3-methyl-1-phenylpyrazolone-5, 1,3-dimethylbarbituric acid, and pyrogallol in the presence of acid to form 4-σ-adducts [7]. Examples of arylation of quinazoline with 1,3,5-trimethoxybenzene, 1-(4-methoxybenzylidene) -2-phenylhydrazine, and o-phenylenediamine derivatives have been described [8].…”

Section: Introductionmentioning

confidence: 99%