Synthesis of stable hollow silica nanospheres

Tan, Ming Ning; Park, Yong Sung

doi:10.1016/j.jiec.2008.11.013

Cited by 18 publications

(5 citation statements)

References 24 publications

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“…M. Tan et al [ 96 ] produced coagulated particles, free solid particles, and smooth surface hollow spheres by changing the volume of TEOS and the ratio of ammonia/TEOS. It was established that TEOS between 1.02 and 1.5% vol was suitable for producing hollow silica nanospheres with a good surface.…”

Section: Polystyrene Coatingmentioning

confidence: 99%

Hollow Silica Nano and Micro Spheres with Polystyrene Templating: A Mini-Review

et al. 2022

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Synthesis of monodisperse hollow silica nanospheres, especially using a hard template route, has been shown to be successful, but a high yield is needed for this strategy to be used on an industrial scale. On the other hand, there is a research gap in the synthesis of hollow silica microspheres due to the popularity and easiness of the synthesis of silica nanospheres despite the larger spheres being beneficial in some fields. In this review, current trends in producing hollow silica nanospheres using hard templates, especially polystyrene, are briefly presented. Soft templates have also been used to make highly polydisperse hollow silica spheres, and complex designs have improved polydispersity. The effect of the main parameters on the coating is presented here to provide a basic understanding of the interactions between the silica and template surface in the absence or presence of surfactants. Surface charge, surface modification, parameters in the sol–gel method and interaction between the silica and templates need to be further improved to have a uniform coating and better control over the size, dispersity, wall thickness and porosity. As larger organic templates will have lower surface energy, the efficiency of the micro sphere synthesis needs to be improved. Control over the physical structure of hollow silica spheres will open up many opportunities for them to be extensively used in fields ranging from waste removal to energy storage.

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Section: Polystyrene Coatingmentioning

confidence: 99%

Hollow Silica Nano and Micro Spheres with Polystyrene Templating: A Mini-Review

et al. 2022

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“…In hard template approach appropriate surface functionalization for interfacial recognition of silicates are to be performed prior to silicification on organic template. Tan et al 20 demonstrated PS as hard-core template for the synthesis of hollow silica nanoparticles. PS hard-core template of size that varies from 350 nm to 450 nm was developed from emulsion polymerization method.…”

Section: Synthetic Approaches Of C/s-msnsmentioning

confidence: 99%

Theragnostic potentials of core/shell mesoporous silica nanostructures

Girija

Balasubramanian

2019

Nanotheranostics

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Theragnostics is considered as an emerging treatment strategy that integrates therapeutics and diagnostics thus allowing delivery of therapeutics and simultaneous monitoring of the progression of treatment. Among the different types of inorganic nanomaterials that are being used for nanomedicine, core shell mesoporous silica nanoparticles have emerged as promising multifunctional nanoplatform for theragnostic application. Research in the design of core/shell mesoporous silica nanoparticles is steadily diversifying owing to the various interesting properties of these nanomaterials that are advantageous for advanced biomedical applications. Core/shell mesoporous silica nanoparticles, have garnered substantial attention in recent years because of their exceptional properties including large surface area, low density, ease of functionalization, high loading capacity of drugs, control of the morphology, particle size, tunable hollow interior space and mesoporous shell and possibility of incorporating multifunctional interior core material. In the past decade researcher's demonstrated tremendous development in design of functionalized core/shell mesoporous silica nanoparticles with different inorganic functional nanomaterial incorporated into mesoporous nanosystem for simultaneous therapeutic and diagnostic (theragnostic) applications in cancer. In this review, we recapitulate the progress in commonly used synthetic strategies and theragnostic applications of core/shell mesoporous silica nanoparticles with special emphasis on therapeutic and diagnostic modalities. Finally, we discuss the challenges and some perspectives on the future research and development of theragnostic core/shell mesoporous silica nanoparticles.

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“…The template-assisted approach is the most used fabrication technique. A suitable organic [ 18 , 19 ] or inorganic [ 20 ] template that will specify the shape and size of the hollow particles is chosen, and the template is coated with silica precursor materials. After silica shell formation, the template is removed, leaving behind the hollow structure.…”

Section: Introductionmentioning

confidence: 99%

Facile Synthesis of Surface-Modified Hollow-Silica (SiO2) Aerogel Particles via Oil–Water–Oil Double Emulsion Method

Kapadnis,

Nam,

Kim

et al. 2024

Gels

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Due to their high surface area and low weight, silica aerogels are ideally suited for several uses, including drug delivery, catalysis, and insulation. Oil–water–oil (OWO) double emulsion is a simple and regulated technique for encasing a volatile oil phase in a silica shell to produce hollow silica (SiO2) aerogel particles by using hydrophilic and hydrophobic emulsifiers. In this study, the oil–water–oil (OWO) double emulsion method was implemented to synthesize surface-modified hollow silica (SiO2) aerogel particles in a facile and effective way. This investigation mainly focused on the influence of the N-hexane-to-water glass (OW) ratio (r) in the first emulsion, silica (water glass) content concentration (x), and surfactant concentration (s) variations. Furthermore, surface modification techniques were utilized to customize the aerogel’s characteristics. The X-ray diffraction (XRD) patterns showed no imprints of impurities except SiO2. Scanning electron microscopy (SEM) and transmission electron microscopy (TEM) images highlight the hollow microstructure of silica particles. Zeta potential was used to determine particle size analysis of hollow silica aerogel particles. The oil–water–oil (OWO) double emulsion approach was successfully employed to synthesize surface-modified hollow silica (SiO2) aerogel particles, providing precise control over the particle characteristics. By the influence of the optimization condition, this approach improves the aerogel’s potential applications in drug delivery, catalysis, and insulation by enabling surface modifications.

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Synthesis of stable hollow silica nanospheres

Cited by 18 publications

References 24 publications

Hollow Silica Nano and Micro Spheres with Polystyrene Templating: A Mini-Review

Hollow Silica Nano and Micro Spheres with Polystyrene Templating: A Mini-Review

Theragnostic potentials of core/shell mesoporous silica nanostructures

Facile Synthesis of Surface-Modified Hollow-Silica (SiO2) Aerogel Particles via Oil–Water–Oil Double Emulsion Method

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