Synthesis of Some Thiosemicarbazone and Oxirane Derivatives as Potent Antitubercular Agents.

Abstract

CHOVATIA, P. T.; JOSHI*, H. S.; J. Indian Chem. Soc. 82 (2005) 10, 940-941; Dep. Chem., Saurashtra Univ., Rajkot 360 005, India; Eng.) -A. Forchert 22-104

10.1007/s11178-008-1014-y

“…Hydrazones having unsaturated fragments, including acetylenic, attract interest as highly reactive building blocks for organic synthesis. A convenient approach to such compounds may be based on reactions of accessible α-acetylenic ketones with thiocarbonohydrazide (thiocarbonic acid dihydrazide) and its derivatives [2,12]. A convenient approach to such compounds may be based on reactions of accessible α-acetylenic ketones with thiocarbonohydrazide (thiocarbonic acid dihydrazide) and its derivatives [2,12].…”