Synthesis of Some Oxazine Compounds Derived from TDI and Schiff Bases

Sadeek, Ghufran Th.; Al-Ajely, Mohammad S; Saleem, Neam H.

doi:10.31080/asms.2020.04.0725

Cited by 2 publications

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“…Recently Seyed Gholamhossein Mansouri et-al have synthesized naphtho[1,2-e] [1,3]oxazines and studied their anticancer and antifungal activity [15]. According to the above utility and applications of this type of heterocyclic compounds and in continuing of our current drug discovery program we have synthesize new 1,3-oxazine derivatives using new route of condensation protocol [16][17][18].…”

Section: Introductionmentioning

confidence: 99%

New Approach for the Synthesis of Aryloxy 1,3-Oxazines

Sadeek¹,

Al-Ajely²,

Saleem³

2020

J Mater Sci Manufac Res

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Oxazinne compounds have drew the attention of many researchers to find different approaches to the synthesis of this type of compounds according to the success of their use in a wide range of pharmaceutical application during the last decades .It is also for the difference reactivity of these analogues is exhaustively depicted and illustrates the rich versatility of this class of starting material. They proved to have most of actions of a combination of other drugs. We are herein investigate the synthesis of ethyl aryloxy acetate(S1-6) from the reaction of the corresponding ethyl bromo acetate with aryl phenols.These intermediates were cyclized with antharanilic acid affording the titled compounds.

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Section: Introductionmentioning

confidence: 99%

New Approach for the Synthesis of Aryloxy 1,3-Oxazines

Sadeek¹,

Al-Ajely²,

Saleem³

2020

J Mater Sci Manufac Res

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Recent Methodologies for the Synthesis and Applications of Oxazine Compounds

Al-Ajely

2021

BJSTR

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In this short review we will concentrate on the newest methods for the synthesis of this type of important heterocyclic compounds. This type of compounds have proved to have valuable pharmaceutical and medical applications as drugs and co drugs for numerous types of diseases starting from microorganism screening to cancer cells treatments and have been succeeded in all types of these therapeutic and medical fields.

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Synthesis of Some Oxazine Compounds Derived from TDI and Schiff Bases

Cited by 2 publications

References 0 publications

New Approach for the Synthesis of Aryloxy 1,3-Oxazines

New Approach for the Synthesis of Aryloxy 1,3-Oxazines

Recent Methodologies for the Synthesis and Applications of Oxazine Compounds

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