Synthesis of some furo‐thiazolidine derivatives starting from aldimines

Abstract

Alkyl and aryl substituted furothiazolidine derivatives have been synthesized by the reaction of Wittig reagent with benzylidene derivatives of 4‐thiazolidinones obtained from aldimines and thioglicolic acid.

Synthesis and Antimicrobial Activities of Some Novel 2,3-Substituted-1,3-Thiazolidin-4-ones Derived from 2-Amino-1,3-thiazole

“…The mixture was refluxed (18)(19)(20) h. After completion of the reaction, the product was cooled to room temperature and the benzene was removed under vacuum [21]. The whole mass treated with saturated solution of sodium bicarbonate until carbon dioxide evolution.…”

“…The traditional methods reported can be either a one-pot three-component condensation [15] or in two-step transform. In the current study, 4-thiazolidinones have been synthesized in two steps, the first step included condensation of substituted-2-naphthaldehyde with various substituted aromatic amines and formation of an imine, which undergoes attack by generated sulfur nucleo-phile, followed by intramolecular cyclization on disposal of water in the second step [16][17][18].…”

Copper/Schiff‐base complex immobilized on amine functionalized silica mesoporous magnetic nanoparticles under solvent‐free condition: A facile and new avenue for the synthesis of thiazolidin‐4‐ones

“…The main synthetic routes for 1,3-thiazolidin-4-ones involve a threecomponent reaction between an amine, a carbonyl compound, and thioglycolic acid. [44][45][46] The newest methodology is synthesis of bis-thiazolidinones through multicomponent reaction of aldehydes, ethylenediamine, and thioglycolic acid using (a) nano-CdZr 4 (PO 4 ) 6 [47] and (b) chitosan-attached nano-CuFe 2 O 4 , [48] and synthesis of oxindole derivatives containing thiazolidinone using nano silica-bonded 5-n-propyl-octahydro-pyrimido [1,2-a] azepiniumchloride via a one-pot reaction of 5-oxoindolinylidene rhodanine-3-acetic acid derivatives, 2-aminothiophenol, and triphenyl phosphite. [49] Mesoporous silicas are inorganic materials formed by the condensation of sodium silicate or silicon alkoxides around an ordered surfactant used as template.…”

Thiazolidine‐4‐ones from Thiocarbohydrazides

“…Their synthesis can be either a one‐pot three‐component condensation or a two‐step process. The reactions involved formation of an imine first, which attacked by sulfur nucleophile, and then, intramolecular cyclization and elimination of water occurred .…”