SYNTHESIS OF SOME DIETHYLPHOSPHONO SUBSTITUTED 2,5-DIHYDROFURAN, 2H-1-BENZOPYRANS AND 3H-NAPHTO[2,1-b]PYRAN

Abstract

The preparation of a.P unsaturated monophosphonate heterocycles is reported. 9-diethylphosphono-7-oxabicyclo[4.3.0]non-1(9)-ene, some 3-diethylphosphono-2H-1-benzopyrans and 2-diethylphosphono-3H-naphtol[2,1-b]pyran have been prepared from tetraethyl ethylidene gem-bisphosphonate and 2-hydrocyclohexanone, substituted salicylaldehydes or 2-hydroxy-1-naphthaldehyde respectively.

Post-polymerization functionalization of linear polyglycidol with diethyl vinylphosphonate

“…[6][7][8][9] An example is the addition of primary or secondary alcohols to a-diethylphosphono-vinylphosphonate (tetraethyl ethylidene gem-bisphosphonate), which proceeds within several minutes. 10 Furthermore, dihydrophilic ionic-nonionic block copolymers derived from poly(ethylene glycol)-block-polyglycidol have been prepared by Penczek et al 11 where the hydroxy groups were reacted with a-ethoxycarbonyl-vinyl-phosphonate (2-diethyl phosphonato ethyl acrylate) and subsequently transformed into carboxylic and phosphonic acid groups.…”

“…hydroxy groups for the double bond of vinyl phosphonates. 6,10 In order to shift the acid-base equilibrium towards the hydroxy groups of polyglycidol the tert-butanol formed was removed under reduced pressure. To minimize precipitation of the potassium alcoholate of PG, potassium tert-butoxide was added dropwise to the solution with a syringe pump.…”