Synthesis of some 2-(4-acetyl-5-aryl-5-methyl-4,5-dihydro-1,3,4-oxadiazol-2-yl)-4-bromophenyl acetate compounds

Abstract

The synthesis of three new 5-bromo-N’-(1-arylethylidene)-2-hydroxybenzohydrazide compounds was accomplished by the use of acid 2-hydroxybenzoic (acid salicylic) as the starting material. Refluxing the hydrazides with acetic anhydride gave three corresponding new compounds namely 2-(4-acetyl-5-aryl-5-methyl-4,5-dihydro-1,3,4-oxadiazol-2-yl)-4-bromophenyl acetates. The structures of the compounds were confirmed by their IR, 1H, 13C-NMR and HR-MS spectral data.