Synthesis of Silver Modified Bioactive Glassy Materials with Antibacterial Properties via Facile and Low-Temperature Route

Gonzalo‐Juan, Isabel; Xie, Fangtong; Becker, Malin; Tulyaganov, Dilshat U.; Ionescu, Emanuel; Lauterbach, Stefan; Rigotti, Francesca; Fischer, Andreas; Riedel, Ralf

doi:10.3390/ma13225115

Cited by 9 publications

(6 citation statements)

References 38 publications

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“…Thus, silver is commonly employed in sensitive health application that requires extreme hygiene, such as artificial implants, surgical instruments, and dental implants [43], or in food and textile industries [40]. Thus, in order to realize multifunctional surfaces with antibacterial features, silver has recently been subjected to much research on its antimicrobial [44], bioactive activities [45], and cytotoxicity features [46].…”

Section: Introductionmentioning

confidence: 99%

Durability of Acrylic Cataphoretic Coatings Additivated with Colloidal Silver

Calovi

Rossi

2022

Coatings

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In this work, colloidal silver has been added into an acrylic clear cataphoretic bath, evaluating the effect of two different filler amounts on the durability of the composite coatings. The three series of samples were characterized by electron microscopy to assess the possible change in morphology introduced by the silver-based additive. The protective properties of the coatings were evaluated by a salt spray chamber exposure and electrochemical impedance spectroscopy measurements, evidencing the negative effect provided by high amount of silver, which introduced discontinuities in the acrylic matrix. Finally, the durability of composite coatings was studied by exposing them to UV-B radiation, observing a strong phenomenon of silver degradation. Although the coating containing high concentrations of silver demonstrated poor durability, this study revealed that small amounts of silver can be used to provide particular aesthetic features, but also to improve the protective performance of cataphoretic coatings.

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Section: Introductionmentioning

confidence: 99%

Durability of Acrylic Cataphoretic Coatings Additivated with Colloidal Silver

Calovi

Rossi

2022

Coatings

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“…Their use is not only limited to health applications but also extends to the food and textile industries [31]. Consequently, following the SARS-CoV-2 pandemic, silver and silver oxide have been subjected to various synthesis studies, analyzing their antimicrobial features [32], cytotoxicity activities [33] and bioactive properties [34].…”

Section: Introductionmentioning

confidence: 99%

Facile Route to Effective Antimicrobial Aluminum Oxide Layer Realized by Co-Deposition with Silver Nitrate

et al. 2021

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The emergence and spreading of the SARS-CoV-2 pandemic has forced the focus of attention on a significant issue: the realization of antimicrobial surfaces for public spaces, which do not require extensive use of disinfectants. Silver represents one of the most used elements in this context, thanks to its excellent biocidal performance. This work describes a simple method for the realization of anodized aluminum layers, whose antimicrobial features are ensured by the co-deposition with silver nitrate. The durability and the chemical resistance of the samples were evaluated by means of several accelerated degradation tests, such as the exposure in a salt spray chamber, the contact with synthetic sweat and the scrub test, highlighting the residual influence of silver in altering the protective behavior of the alumina layers. Furthermore, the ISO 22196:2011 standard was used as the reference protocol to set up an assay to measure the effective antibacterial activity of the alumina-Ag layers against both Gram-positive (Staphylococcus aureus) and Gram-negative (Escherichia coli) bacteria, even at low concentrations of silver. Finally, the Ag-containing aluminum oxide layers exhibited excellent antimicrobial performances also following the chemical–physical degradation processes, ensuring good durability over time of the antimicrobial surfaces. Overall, this work introduces a simple route for the realization of anodized aluminum surfaces with excellent antibacterial properties.

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“…The drug incorporation process on the surface of biomaterials can occur in different ways; among them, sonochemical processing stands out [ 31 ] because in this technique, the ultrasound equipment generates the formation of bullous cavitations through radiation contact with the material [ 46 ], promoting changes in the physical and structural characteristics of the biomaterial, such as reduction, homogenization of particles, and occasionally the formation of a superficial amorphous layer [ 46 , 47 ], which is necessary for the incorporation of the drug. Gonzalo-Juan et al [ 48 ] used the sonochemical technique to produce silver nanoparticles and incorporate them into the surface of the bioglass and proved that this technique does not interfere with the bioactivity mechanisms of glass, as it does not significantly change the network structure of the glass, considering this easy and fast route.…”

Section: Introductionmentioning

confidence: 99%

The Local Release of Teriparatide Incorporated in 45S5 Bioglass Promotes a Beneficial Effect on Osteogenic Cells and Bone Repair in Calvarial Defects in Ovariectomized Rats

Araújo

Silva

Lima

et al. 2023

JFB

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With the increase in the population’s life expectancy, there has also been an increase in the rate of osteoporosis, which has expanded the search for strategies to regenerate bone tissue. The ultrasonic sonochemical technique was chosen for the functionalization of the 45S5 bioglass. The samples after the sonochemical process were divided into (a) functionalized bioglass (BG) and (b) functionalized bioglass with 10% teriparatide (BGT). Isolated mesenchymal cells (hMSC) from femurs of ovariectomized rats were differentiated into osteoblasts and submitted to in vitro tests. Bilateral ovariectomy (OVX) and sham ovariectomy (Sham) surgeries were performed in fifty-five female Wistar rats. After a period of 60 days, critical bone defects of 5.0 mm were created in the calvaria of these animals. For biomechanical evaluation, critical bone defects of 3.0 mm were performed in the tibias of some of these rats. The groups were divided into the clot (control) group, the BG group, and the BGT group. After the sonochemical process, the samples showed modified chemical topographic and morphological characteristics, indicating that the surface was chemically altered by the functionalization of the particles. The cell environment was conducive to cell adhesion and differentiation, and the BG and BGT groups did not show cytotoxicity. In addition, the experimental groups exhibited characteristics of new bone formation with the presence of bone tissue in both periods, with the BGT group and the OVX group statistically differing from the other groups (p < 0.05) in both periods. Local treatment with the drug teriparatide in ovariectomized animals promoted positive effects on bone tissue, and longitudinal studies should be carried out to provide additional information on the biological performance of the mutual action between the bioglass and the release of the drug teriparatide.

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Synthesis of Silver Modified Bioactive Glassy Materials with Antibacterial Properties via Facile and Low-Temperature Route

Cited by 9 publications

References 38 publications

Durability of Acrylic Cataphoretic Coatings Additivated with Colloidal Silver

Durability of Acrylic Cataphoretic Coatings Additivated with Colloidal Silver

Facile Route to Effective Antimicrobial Aluminum Oxide Layer Realized by Co-Deposition with Silver Nitrate

The Local Release of Teriparatide Incorporated in 45S5 Bioglass Promotes a Beneficial Effect on Osteogenic Cells and Bone Repair in Calvarial Defects in Ovariectomized Rats

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