Synthesis of Silica-Coated Magnetic Hydroxyapatite Composites for Drug Delivery Applications

Synthesis of magnetite/silica nanocomposites from natural sand to create a drug delivery vehicle

“…Moreover, the silica surface is chemically stable and biocompatible and can be easily functionalized for bioconjugation [24]. Silica coating of materials has been successfully applied in the fields of optics, erosion resistance, biosensing, biocatalysts, and biomedical devices [25,26,27,28,29]. Silica is not only a stabilizing factor but also provides sites for surface treatment with various ligands that are susceptible to the development of a drug delivery vehicle [26].…”

Multilayered composite-coated ionically crosslinked food-grade hydrogel beads generated from algal alginate for controlled and sustained release of bioactive compounds

“…Surface coating is one of the extensively used strategies to manipulate and modify the performance of carriers for delivery of bioactive agents. 25 By taking advantage of the accumulated knowledge of surface coating techniques, as well as the unique advantage of our coating strategy in which the coating process does not rely on interactions between the core and the coating agent, our method can be easily applied to any coating materials (ranging from chitosan to carboxymethyl cellulose) that can undergo ionic gelation without requiring much consideration of the chemical properties and surface charge of the core. In this study, the formation of droplets of the algal alginate solution relies solely on jet breakup caused by Rayleigh-Plateau instability, along partly with the high viscosity of the coating agent and the resulting thick coating layer, the size of the generated hydrogel beads is in the millimeter-size range and can hardly be further reduced to the micron scale.…”

Mesoporous silica dispersed Co3O4-CuO nanocomposite and its catalytic reduction of 4-nitrophenol

“…Mesoporous silica is widely used in various fields such as drug delivery [20][21][22], adsorption and separation [23,24], and heterogeneous catalysts [25][26][27][28][29], due to its stable physicochemical properties, non-toxicity, low cost, high specific surface area, high pore volume, easy surface modification, good adsorption capacity and continuously adjustable pore size, etc. So as a support for metal oxides, mesoporous silica is an excellent candidate.…”