Synthesis of semicarbazide catechol derivative as a potential electrode modifier: application in electrocatalysis of catechol amine drugs

Hasanpour, Foroozan; Nekoeinia, Mohsen; Semnani, Abolfazl; Shirazinia, Rana

doi:10.1007/s11696-019-00764-3

Cited by 5 publications

(12 citation statements)

References 29 publications

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“…The shift to a short wavenumber (red-shift) and the broadness of these bands confirmed the formation of a cyclized product between catechol and semicarbazide. 7,8,10,13,17,19,22,23 Furthermore, the disappearance of semicarbazide and catechol bands at 2920 cm −1 , 2868 cm −1 , and 2670 cm −1 in the spectrum of product 9 is referred to as the cyclization between catechol and semicarbazide to form the new product. 8–10,13,15,17,19,23…”

Section: Resultsmentioning

confidence: 99%

“…7,8,10,13,17,19,22,23 Furthermore, the disappearance of semicarbazide and catechol bands at 2920 cm −1 , 2868 cm −1 , and 2670 cm −1 in the spectrum of product 9 is referred to as the cyclization between catechol and semicarbazide to form the new product. 8–10,13,15,17,19,23…”

Section: Resultsmentioning

confidence: 99%

“…The shift to long wavenumber and sharpness of the band at 519 cm −1 could be assigned to the N–H deformation of the cyclized ring formed in the product ( 9 ). 8–10,13,15,17,19,23…”

Section: Resultsmentioning

confidence: 99%

“…The proton NMR spectrum of adduct 9 (Fig. 8) showed accompanying broad bands at chemical shift ( δ 5.93–6.03 ppm) could be assigned to two NH protons 23,52–56 of the novel triazinone ring. Similarly, 2 accompanied OH protons exist as a broad peak at chemical shift ( δ 7.50 ppm) formed merged with a third amidic NH proton at δ 7.80 ppm.…”

Section: Resultsmentioning

confidence: 99%

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Green electro-organic synthesis of a novel catechol derivative based on o-benzoquinone nucleophilic addition

et al. 2023

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

“…The shift to long wavenumber and sharpness of the band at 519 cm −1 could be assigned to the N–H deformation of the cyclized ring formed in the product ( 9 ). 8–10,13,15,17,19,23…”

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

See 2 more Smart Citations

Green electro-organic synthesis of a novel catechol derivative based on o-benzoquinone nucleophilic addition

et al. 2023

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“…The FTIR spectral data of compounds 1b-3b show the disappearance of the absorption band at 1753 cm -1 , which belongs to ν (C=O) of the ester. There is a new absorption band at 1695-1664 cm -1 which belongs to ν (C=O) of the amid band (1) [26]. There are also new absorption bands at 3468-3438 cm -1 and 3417-3398 cm -1 which belong to ν (NH 2 ) Asym.…”

Section: Scheme (1)mentioning

confidence: 94%

Synthesis and Identification of Some New Derivatives of ([Benzyl Thio) Benzimidazole -N- (Methylene-5-Yl)] - 4,5- Di Substituted 1,2,4-Triazole and Evaluation of Their Activity as Antimicrobial and Anti-Inflammatory Agents

Suaad

Halah

Yasser

2021

eijs

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New 2-Mercaptobenzimidazole derivatives were synthesized. 4,5-disubsitituted 1,2,4-Triazole compounds 1b-2c were synthesized from 2-(benzylthio) benzimidazole compound a, which was then reacted with (NaH) in dioxane at a temperature of (0-5 C°) to produce the salt of compound a. Then the salt was reacted with ethyl chloro acetate to yield Ethyl 2-(benzylthio) benzimidazole acetate compound b. Compound b was converted to triazole derivatives by two pathways. The first pathway was reacting compound b with semicarbazide, thiosemicarbazide and phenylsemicarbazide in DMSO as a solvent to gain compounds 1b-3b, which were then cyclized by refluxed with 2N (NaOH) to yield 1,2,4-triazole derivatives compounds 4b-6b. The second pathway involved the treatment of compound b with hydrazine hydrate to produce N-acetohydrazide-2-(benzyl thio) benzimidazole c. Compound c was refluxed with carbon disulfide (CS2) in KOH alcoholic solution to obtain the salt compound 1c. The salt was treated with hydrazine hydrate to yield 1,2,4-triazole derivative compound 2c. The newly synthesized compounds b-2c were identified by FTIR, 1H-NMR and 13C-NMR and their physical properties were measured. Furthermore, their anti-microbial activities were tested against two Gram-positive and two Gram-negative bacteria and against one strain of fungi. Also, some of these synthesized compounds were tested for their anti-inflammatory activities.

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Magnetically aligned graphite flakes electrodes for excellent sensitive detection of hydroquinone and catechol

Song

et al. 2022

Chem. Pap.

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Synthesis of semicarbazide catechol derivative as a potential electrode modifier: application in electrocatalysis of catechol amine drugs

Cited by 5 publications

References 29 publications

Green electro-organic synthesis of a novel catechol derivative based on o-benzoquinone nucleophilic addition

Green electro-organic synthesis of a novel catechol derivative based on o-benzoquinone nucleophilic addition

Synthesis and Identification of Some New Derivatives of ([Benzyl Thio) Benzimidazole -N- (Methylene-5-Yl)] - 4,5- Di Substituted 1,2,4-Triazole and Evaluation of Their Activity as Antimicrobial and Anti-Inflammatory Agents

Magnetically aligned graphite flakes electrodes for excellent sensitive detection of hydroquinone and catechol

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