Synthesis of Schiff Bases Derivatives from Benzene Diamine Containing Acridine Moiety

Abstract

One side of (o, m and p) benzene diamine reacted with aromatic aldehyde to give Schiff bases (Ia-d) or (IIa-d) and (IIIa-d) respectively. The second amine group of the synthesized Schiff bases (Ia-d or IIa-d and IIIa-d) was reacted with substituted-9-chloroacridine to give the final compounds namely N-(Substituted benzylidene)-N'-(Substituted acridine-9-yl) (1,2 or 1,3 and 1,4) benzene diamine (V,VI,VII).The reaction progress was followed by thin layer chromatography (TLC), and R f values were recorded. I.R. Spectral data for all the synthesized derivatives were reported. The U.V-Vis., and the 1 HNMR(300and 400MHz) were recorded for some derivatives to support the structure of the synthesized compounds.