Synthesis of rare nucleobases and artificial nucleotides for investigation of catalytic enzyme activity

Abstract

Structural insights into the stimulation of S. pombe Dnmt2 catalytic efficiency by the tRNA nucleoside queuosine", Scientific Reports, 2018, 8:8880. Declaration of AuthorshipHereby, I declare that I prepared the doctoral thesis entitled "Synthesis of rare nucleobases and artificial nucleotides for investigation of catalytic enzyme activity" on my own and with no other sources and aids than quoted.Göttingen, August 2019 MATTHIAS KRULL Dedicated to my parents 3.5.9. 2',3'-O-Isopropylidene-queuine (144) .