Abstract:In this paper, a series of 13-aryl-6,13-dihydro-3H-quino[4,3-b]pyrrolo[3,2-f]quinolin-12(11H)-one derivatives was synthesized in EtOH under catalyst-free conditions using aromatic aldehydes, 5-aminoindole and 4-hydroxyquinolin-2(1H)-one as reactants. The structure of 4b was confirmed by X-ray diffraction analysis. This procedure has the advantages of simplicity and easy operation. An efficient method for the synthesis of fused pentacyclic heterocycles containing biquinolines moieties is provided.
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