Synthesis of Quinazolinones Via a Tandem Hydrogen-Transfer Strategy Catalyzed by N,S Co-doped Carbon-Anchored Co Nanoparticles

Abstract

A N,S codoped carbon-anchored Co nanoparticle (NP) material (Co@NSC-1) has been developed via the pyrolysis of the mixture of Co/Zn–zeolitic imidazolate frameworks (ZIFs) and thiourea. This catalyst exhibits excellent catalytic activity for the synthesis of quinazolinones from 2-nitrobenzonitrile and benzyl alcohol under additive-free conditions. The superior activity is mainly attributed to the dispersed Co NPs, large specific surface areas, strong acid–base sites, and the synergistic effects between cobalt NPs and doping of N,S atoms. It is worth noting that Co NPs are protected by the N,S codoped carbon shells of this catalyst, so it displays no significant loss in activity after six runs.

Nitrogen and Phosphorus Dual-Coordinated Single-Atom Mn: MnN2P Active Sites for Catalytic Transfer Hydrogenation of Nitroarenes

“…Among the various hydrogen donors, formic acid (FA), an easily handled and less toxic liquid, is a more green and sustainable alternative which can be decomposed and generate CO 2 during the catalytic process. , In fact, a significant number of protocols using FA have emerged, but the applications of homogeneous catalysts are limited by the difficulty of separation and recycle. − To date, some examples of the CTH of nitroarenes catalyzed by heterogeneous catalysts have been reported, which have overcome the shortcoming of low efficiency. Among them, most examples are performed over noble metal catalysts such as Pd, Au, and Pt .…”

Synthesis of Nitrogen- and Oxygen-Containing Heterocycles Catalysed by Metal Nanoparticles Reported in 2022

“…A tandem hydrogen-transfer strategy from substituted 2-nitrobenzonitrile (59) and substituted benzyl alcohols (60) under the additive-free conditions (Scheme 15) in toluene at 140 °C used the carbon-supported Co heterogeneous catalyst (Co@NSC-1) containing dispersed CoNPs and the N,S codoped carbon support to produce quinazolinones (61). 69 The pyrolysis of Co/Zn, zeolitic imidazolate frameworks (ZIFs), and thiourea produced the catalysts, which were then studied using SEM, TEM, XRD, HR-TEM, EDX, XPS, and other techniques. These catalysts showed excellent catalytic activity through their extended surface areas and strong acidic-basic sites for interactions, and they could be reused up to six times.…”

Eco‐sustainable Synthesis of N‐containing Heterocyclic Systems Using Porous Carbon Catalysts

“…On the other side, Su et al [145] prepared an active catalyst, composed by Co nanoparticles (as Co 0 , Co 3 + , CoÀ N x , Co 2 + species) encapsulated into N,S dual-doped CNT shells (Co@NSC-1), obtained by pyrolysis of a mixture of Co/ZnÀ ZIF-8 and thiourea at 900 °C. The catalyst was studied in the synthesis of quinazolinones from benzyl alcohol and 2-nitrobenzonitrile at 140 °C in absence of any additive (Scheme 30).…”

“…On the other side, Su et al [145] . prepared an active catalyst, composed by Co nanoparticles (as Co 0 , Co 3+ , Co−N x , Co 2+ species) encapsulated into N,S dual‐doped CNT shells (Co@NSC‐1), obtained by pyrolysis of a mixture of Co/Zn−ZIF‐8 and thiourea at 900 °C.…”