Synthesis of Pyrimidine Derivatives Catalyzed by Nanomagnetic Pyridinium‐Tribromide Ionic Liquid

Abstract

Some novel pyrimidine derivatives are prepared via one-pot reaction of triethoxymethane, aromatic ketone and ammonium acetate using catalytic system including nano-magnetic pyridinium-tribromide (TBP-SCMNPs). The synthesized new catalyst was characterized by FE-SEM, EDS, TEM, XRD, and TGA analysis. The highlighting points of using TBP-SCMNPs are easy purification, reusability of the catalyst, good yields of products with short time reactions.

Influence of ionic liquid counterions on activity and selectivity of ethylene trimerization using chromium‐based catalysts in biphasic media

“…[24,25] The liquid-liquid biphasic catalysis system has received much attention, and the possibility of using this technology in industrial processes is being investigated by many researchers. [15,26] In recent decades the ILs have attracted much attention because of their extensive applications in organic synthesis, [27][28][29][30][31][32][33] catalytic oligomerization of ethylene, [4,17,25] chemical separation, [34][35][36] material, and energy science. [37,38] For example, the chloroaluminate IL has been used as solvents in ethylene oligomerization reactions in the presence of nickel complexes to overcome the deactivation of the catalyst.…”

A decennary update on applications of metal nanoparticles (MNPs) in the synthesis of nitrogen- and oxygen-containing heterocyclic scaffolds

“…222 Recently, they also reported pyridinium tribromide ionic liquid-supported silica coated ferrite NPs for the efficient synthesis of 4-phenyl pyrimidines from triethoxy methane, ammonium acetate and substituted acetophenones. 223 Yavari et al reported the synthesis of 2-aryl imidazoles (83g)/ benzothiazoles (204a)/benzimidazoles (83h)/spermidine (206) derivatives via cyclocondensation with aromatic aldehydes catalyzed by functionalized magnetic core NPs (Fe 3 O 4 /SiO 2 / (CH 2 ) 3 N + Me 3 Br 3 ) under solvent-free conditions at 80 C in 89-95% yield (Scheme 108). 224 The NPs were prepared via the coprecipitation of ferrous (FeSO 4 $7H 2 O) and ferric salts (FeCl 3 -$7H 2 O) with NH 4 OH followed by coating with silica using the Stöber process, graing with aminopropylsilanes and coupling with methyl iodide and tribromide (KBr/Br 2 ).…”

Synthesis of multiple quinoline derivatives using novel ionic liquid-based nano-magnetic catalyst (MNPs@SiO2-Pr-AP-tribromide)

“…The catalyst had a good reactivity due to the appropriate concentration of bromine and had little degradation during the reaction. Then from ionic liquid-based nano-magnetic (MNPs@SiO 2 -Pr-AP-tribromide) [53] to synthesize quinoline derivatives 3(a-i), we used a one-pot reaction between 2-amino aryl ketones (1) and carbonyl compounds (2) (Scheme 1).…”