Synthesis of pyrazole-4-carbonitrile derivatives in aqueous media with CuO/ZrO2 as recyclable catalyst

Ag/SiO2 as a recyclable catalyst for the facile green synthesis of 3-methyl-4-(phenyl)methylene-isoxazole-5(4H)-ones

“…MCRs allow three or more compounds to react together, providing products in high yields without having to isolate intermediates. This is an attractive option [1][2][3], thus making MCRs an important tool in the synthesis of heterocyclic molecules with combinatorial, medicinal and agricultural chemistry applications [3][4][5]. The other advantages of these reactions include high bond-forming efficiency, cost effectiveness, energy saving and simple workup procedures [6,7].…”

Reusable Ce‐V Loaded Alumina Catalyst for Multicomponent Synthesis of Substituted Pyridines in Green Media

“…In continuation of our research work in the domains of MCRs herein, we report a novel, environmentally benign, a facile and efficient method for the first time of the use of Ce‐V/Al 2 O 3 as heterogeneous catalyst to promote a fast MCR protocol for the synthesis of polysubstituted pyridines at room temperature (R.T.) in eco‐friendly in aqueous ethanol media (Scheme ).…”

Ultrasound mediated green synthesis of pyrano[2,3-c]pyrazoles by using Mn doped ZrO2

“…In continuation of our previous research toward the improvement of new green routes for the synthesis of heterocyclic compounds using reusable catalysts 2013b); Maddila et al, (2013a;2015a;2015b;2015c;2016a;2016b)), we report herein, the application of a novel recyclable heterogeneous solid catalyst (Mn supported zirconium (Mn/ZrO 2 )) under ultra-sonication for efficient, convenient and facile green synthesis of various pyranoyrazole derivatives through the one-pot reaction of dimethyl acetylenedicarboxylate (or) ethyl acetoacetate, hydrazine hydrate, malononitrile and aldehyde under aqueous ethanol solvent condition and at room temperature. In addition, to the best of our knowledge, there are no reports on the use of Mn supported ZrO 2 as a heterogeneous catalyst under ultra-sonication for this conversion.…”