Synthesis of Polystyrene and Molecular Weight Determination by ¹H NMR End-Group Analysis

Abstract

A procedure for the solution polymerization of styrene using di-tert-butyl peroxide (DTBP) as the initiator is described. The use of DTBP allows for end-group analysis by 1H NMR spectroscopy and calculation of the number-average molecular weight of the polymer. This experiment was designed as a laboratory introduction to polymer chemistry for second-year undergraduate students. The highest-order focus was to get students to derive an equation to calculate the number-average molecular weight by 1H NMR spectral analysis.

Co-delivery of doxorubicin and conferone by novel pH-responsive β-cyclodextrin grafted micelles triggers apoptosis of metastatic human breast cancer cells

“…Therefore, Eqs. ( 4 ) and ( 5 ) were used for determining molar mass (M n ) of β CD-g-PMA-co-PLGA , with the aid of integrating of the peaks in 1 HNMR spectrum 25 . …”

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“…Furthermore, because of the vigorous interaction of hydroxyls of the βCD with the GPC column, other researchers have also reported problems with calculating the molecular weight of their polymer by GPC [13,24]. Therefore, Equations 4 and 5 were used for determining molar mass (Mn) of βCD-g-PMA-co-PLGA, with the aid of integrating of the peaks in 1 HNMR spectrum [25].…”

Styrenated Oil Synthesis with Cyclic Carbonate Functional Groups on Polystyrene Segment

“…Additionally, the peaks at 4.82 and 4.55–4.35 ppm correspond to the protons of the cyclic carbonate groups of AGC [ 48 , 52 , 54 ]. The other peaks at 0.8–2.4 ppm represent the aliphatic -C H -, C H 2 -, and C H 3 protons of the polymer [ 44 , 50 , 55 ]. The intensive peaks of vinyl groups of styrene and allyl groups of AGC appear in the range of 5–6.5 ppm [ 45 , 50 ].…”