Synthesis of Photosensitive Cyclopropane-Containing Polymers

Guliyev, K. G.; Rzayeva, A. E.; Guliyev, A. M.

doi:10.1134/s1070427219090052

Cited by 3 publications

(2 citation statements)

References 8 publications

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“…Various light sensitive polymers e.g. polymer containing diazonaphtoquinones, azobenzene, cyclopropane containing polymers are synthesized and applied for the surface modification of liposomes to get photosensitive nature of liposomes [126][127][128][129][130]. Photosensitive liposomes have been applied to deliver varieties of molecules including drugs, nanoparticles, etc.…”

Section: Types Of Liposomesmentioning

confidence: 99%

Liposomes-The 21st Century’s Drug Delivery System: Developments in the Last Two Decade

Adhikari

2023

ajc

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Liposomes have been thoroughly investigated and are utilized for various illnesses for the past few decades starting from its first discovery in 1961. Since then, therapeutic efficiency of liposomes is enhanced by increasing drug absorbance while fast deterioration and adverse effects are avoided or minimized. This will extend the biological halfway life. Liposomes are more attractive for usage as drug delivery carriers with all of these characteristics and versatility to modify their surface to create additional specific functionalities. In various phases of research, there are numerous new liposomal compositions that improve the therapeutic efficiency of new and old medicines used in pre-clinical and clinical studies. Current multimodal imaging advances aimed at better diagnosing and monitoring liposome therapies as diagnostic tools. Liposomes are major possibilities for medication delivery improvement. Recent researches show that the liposomes can be taken widely in cancer treatments. The primary properties of these structures include minimal toxicity, cytocompatibility, reduced clearance rates, tissue targeting and sustained drug release. Liposomes offer a variety of benefits as shown by approval of Doxil, as compared to traditional chemotherapy with free medication treatment. There are a multitude of liposomes depending on their size, lamellar number, shape and composition. Diagnostic, therapeutic, improved vaccination are covered by clinical use of these systems. Drug and gene delivery are two therapeutic aspects, where due to their unique characteristics liposomes might be beneficial. Several illnesses have been examined with respect to the participation of liposomes, with some good results. Cancer is a life-threatening disease. These structures have been examined in this respect, both in imaging and in chemotherapy. These investigations have resulted in different liposome compositions in different clinical stages. We take this great opportunity to present various surface functionalization strategies and bio-applications of liposomes developed during the last two decades covering the notable work published from 2011 to 2021 in this review. In addition, we provide opinions on the liposome industry, its commercial market and the prospective developments in the field of liposome technology. It is anticipated that this review will serve as a valuable resource, fostering interest and engagement among scientists worldwide in the field of liposome research.

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Section: Types Of Liposomesmentioning

confidence: 99%

Liposomes-The 21st Century’s Drug Delivery System: Developments in the Last Two Decade

Adhikari

2023

ajc

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“…Cyclopropane-containing compounds are known to be effective and relatively safe biocides with high biological activity [13][14][15][16][17][18]. Scientific research aimed at the development of new effective methods of obtaining polymers possessing a complex of predetermined properties retains its relevance.In this connection, it is interesting to study the reactions of radical copolymerization of new binary systems, with specified complex properties, including particularly high biocidal activity of the synthesized copolymer.…”

Section: Introductionmentioning

confidence: 99%

Synthesis of Para-Aminophenyl Cyclopropylmethacrylate and Its Radical Copolymerization With Styrene

Vahabova¹,

Mammadova²,

Guliyev³

2023

AChJ

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The synthesis of a new monomer para-aminophenyl cyclopropyl methacrylate (APCM) was carried out, its radical copolymerization with styrene was investigated and some regularities of the process were studied. Its radical copolymerizations with styrene were carried out and the resulting copolymers were established in the structures. Based on the IR-NMR and UV spectra, it was found that the copolymerization process of para-aminophenyl cyclopropyl methacrylate proceeds through the double bond, and the substituents, para-aminophenyl cyclopropyl fragment, remain in the side macrochain. The values of the relative activity constants of monomer were determined and the parameters Q and e were calculated according to Alfrey and Pras. The copolymerization constants of the specified compound (r1) with styrene (r2) calculated by the Feinman-Ross method are r1=0.45, r2=0.22, the values of parameters Q and e: Q=0.024 and e=-2.316, respectively. It was revealed that the resulting copolymer has a sufficiently high biomedical activity, which opens the possibility of using this copolymer as a bactericide

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Synthesis of Photosensitive Styrene Copolymers with p-Phenyl-Substituted Cyclopropyl Methacrylates

et al. 2021

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Synthesis of Photosensitive Cyclopropane-Containing Polymers

Cited by 3 publications

References 8 publications

Liposomes-The 21st Century’s Drug Delivery System: Developments in the Last Two Decade

Liposomes-The 21st Century’s Drug Delivery System: Developments in the Last Two Decade

Synthesis of Para-Aminophenyl Cyclopropylmethacrylate and Its Radical Copolymerization With Styrene

Synthesis of Photosensitive Styrene Copolymers with p-Phenyl-Substituted Cyclopropyl Methacrylates

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