Synthesis of Phosphachromones by Cyclized Coupling of Ethyl Hydrogen (Phenylethynyl)phosphonate with Arynes

Abstract

A straightforward and efficient strategy for the synthesis of phosphachromones has been reported via the insertion of arynes into P−O bonds. This operationally simple reaction is compatible with different functional groups, affording various phosphachromones by the simultaneous formation of C−P and C−O bonds in one step with moderate to good yields, and the Fries rearrangement involving phosphorus atoms is a key step in the reaction.