Synthesis of orthogonally protected l-glucose, l-mannose, and l-galactose from d-glucose

Construction of 4‐(Methylthio)isochromenones Skeleton through Regioselective Intramolecular Cyclization of 2‐Alkynylbenzoate Mediated by DMSO/[D6]DMSO and SOCl2

“…[13,[23][24][25][26][27][28][29][30][31][32][33][34][35][36][37] Meanwhile, diverse substituents can be introduced at the 4-position of the isochromenones. [13,[32][33][34][35][36][37][38] Although C sp 2 -S bond formation had been widely reported, [39][40][41][42][43][44][45][46][47][48] the preparation of 4-sulfenylisochromenones has been less explored due to the limitation on their synthetic strategies. Larock and co-workers [35] reported that by treating alkynes with the electrophilic sulfenyl chloride, sulfoesterification occurred to give the corresponding 4-(sulfenyl)isochromenones (Scheme 1a).…”

“…Larock and co-workers [35] reported that by treating alkynes with the electrophilic sulfenyl chloride, sulfoesterification occurred to give the corresponding 4-(sulfenyl)isochromenones (Scheme 1a). Zeni [33] and Zhou [34] groups developed a FeCl 3 -promoted intermolecular sulfoesterification of 2alkynylbenzoates using disulfides as the sulfur source [ philic 6-endo-dig cyclization. DMSO plays the roles of both solvent and sulfur source and can also be replaced with its deuterated counterpart [D 6 ]DMSO, enabling the incorporation of the SCD 3 moiety into the isochromenone skeleton.…”

“…[38] Although these 4-sulfenylisochromenones with different substitution patterns have been successfully synthesized, there are few reports on the construction of isochromenone skeleton bearing the biological interesting methylthio substituent in its 4-position. [33,34] The methylthio group and its derivatives including methyl sulfoxide and methylsulfone are interesting substituents found in many biologically active pharmaceutical agents, such as Omeprazole, [49] Rabeprazole, [50] Thiamphenicol, [51] and Sulindac (as a prodrug) [52] (Figure 1). Therefore, development of novel method for synthesis of 4-(methylthio)isochromenone, an exclusive class of 4-sulfenylisochromenones, should be able to attract a great deal of interest from both organic and medicinal chemists.…”

Wide range humidity sensors printed on biocomposite films of cellulose nanofibril and poly(ethylene glycol)

“…8,9 CNF films exhibit interesting mechanical properties, have low oxygen permeability, are translucent and can absorb large quantities of liquid. 18,20 Such biodegradable and environmentally benign materials are crucial for realization of the concept of so-called "transient electronics," 21 which addresses the issue of growing global e-waste production 22 and consumption of scarce sources of noble metals and other precious materials. 16 Smooth CNF films have also potential as substrate for printing conductive structures and transistors.…”

A mild and efficient method for the selective cleavage of primary p-methoxybenzyl protecting group of saccharides by Co2(CO)8–Me2PhSiH–CO system

“…Solvents, temperature, and equivalents of Co 2 (CO) 8 were then screened. 16 Optimal result was achieved using 0.5 equiv of Co 2 (CO) 8 and 20 equiv of Me 2 PhSiH in refluxing CH 2 Cl 2 (entry 11), which yielded the de-6-O-PMB product (1b) in 86%. Lowering the temperature or reducing the equivalent of Me 2 PhSiH can decrease the yield of 1b, while a large amount of 1a was not consumed after stirring for 48 h (entries 12 and 14).…”