Synthesis of Novel Thiazole Based Carbaldehyde as Potential Sensor for Fluoride Anion and their Spectroscopic Properties

Abstract

A novel thiazole based carbaldehyde bearing benzimidazole fluorophore as the receptor unit for F anion was prepared by multi steps synthesis. Density functional theory was used to understand the structural and electronic properties the receptor. The anion sensing activities of receptor 4 were studied for various anions in acetonitrile solvent. The receptor showed fluorescence enhancement in the presence of fluoride anion due to intramolecular charge transfer (ICT) mechanism. No significant changes were observed upon addition of less basic anions such as OAc, Cl, Br, I, HSO. After the interaction of fluoride anion with the receptor 4 leads to an 88 nm red shift in emission maxima. [TBA]OH and H NMR titration experiments indicated that deprotonation of N-H in the benzimidazole due to interaction with fluoride anions.

A Simple and Efficient Schiff Base Derived Chemosensor for Selective Detection of Fluoride Ion

“…In summary we have designed and synthesized a thiazole based molecule which functions as fluoride ion sensor. The chemosensor 1 was characterized by 1 H NMR, 13 C NMR and UV-vis spectroscopy. The chemosensor 1 shows high selectivity towards fluoride ions.…”

“…All the HPLC grade solvents were purchased from Spectrochem, India and used without further distillation. The 1 H NMR and 13 C spectra were recorded on Bruker, Avance II (400 MHz)…”

“…12 Thiazole and their derivatives are found in many natural and synthetic products, display variety of applications and are mainly used pharmacology studies as well as for several sensing applications. [13][14][15][16][17][18][19][20] In the present work, we report the synthesis, photophysical and fluoride detection properties of the…”