Synthesis of novel reactive N-halamine precursors and application in antimicrobial cellulose

Electrospun non-leaching biocombatible antimicrobial cellulose acetate nanofibrous mats

“…Moreover, N-halamines inactivate bacteria and viruses rapidly without producing antimicrobial resistance. N-halamines have been widely used in textiles, medical devices, and water treatment as antimicrobial materials [10,[16][17][18][19][20][21][22].…”

“…Moreover, N-halamines inactivate bacteria and viruses rapidly without producing antimicrobial resistance. N-halamines have been widely used in textiles, medical devices, and water treatment as antimicrobial materials [10,[16][17][18][19][20][21][22].According to the antibacterial mechanism of N-halamines, bacteria must contact the surface of the antibacterial materials in order to inactivate the bacteria, and the antibacterial efficacy relies on the contact surface area between the bacteria and biocidal materials. N-halamine-based biocidal materials containing larger surface areas can provide more N-halamine functional sites to kill bacteria and improve antibacterial efficacy.…”

“…The antimicrobial materials used in our daily life such as in water purification systems, textile materials, food packaging and storage, and medical devices could protect our health. Quaternary ammonium salts [1,2], metal ions and metal oxides [3], chitosan [4][5][6], citric acid derived polymers [7], and N-halamine compounds [8][9][10][11][12][13][14][15] have been used as biocidal materials generally. Among these, N-halamines are desired biocides due to their excellent biocidal efficacies, no toxicity to animals and humans, regenerabilities, stabilities and durabilities.…”

Synthesis of polysiloxane with 5,5‐dimethylhydantoin‐based N‐halamine pendants for biocidal functionalization of polyethylene by supercritical impregnation

“…Surface modification of polymers with antibacterial groups such as N ‐halamines, quaternary ammonia salts, and heavy‐metal ions is an efficient means to avoid the growth of microorganisms and provide extended applications in biomaterials and daily life. PE is the most commonly used plastic due to its many attractive properties including flexibility, nontoxicity, high strength, and chemical stability.…”

Preparation of antibacterial cellulose with s‐triazine‐based quaternarized N‐halamine

“…In our previous studies, several N‐ halamine precursors based on s‐triazine were synthesized and then applied on cotton fabrics with exhaustion process . These compounds had good solubility in water from the introduction of sulfonic group, and the treated fabrics showed good antimicrobial properties against Staphylococcus aureus and Escherichia coli O157:H7.…”