“…For background to pyrazole-based ligands, see; Ahmed et al (2005); Abonia et al (2002Abonia et al ( , 2004Abonia et al ( , 2010; Guerrero et al (2009); Quiroga et al (2008); Schutznerová , et al (2012). For structure of an isomer of the title compound, see: Low et al (2004).…”
Section: Related Literaturementioning
confidence: 99%
“…As a part of our current research work focused on the development of new bioactive heterocyclic compounds and continuing with the use of pyrazolic Schiff bases (Quiroga et al, 2008;Abonia et al 2002Abonia et al , 2004Abonia et al , 2010, in the synthesis of pyrazolopyrimidines, we want to describe the compound 5-amino-3-tert-butyl-1-(3-nitro-phenyl)-1H-pyrazole (I), which is a structural isomer of a related compound previously reported by Low (Low et al, 2004).…”
In the title compound, C13H16N4O2, the pyrazole ring forms a dihedral angle of 50.61 (6)° with the 3-nitro-phenyl ring. The plane of the nitro group is twisted by 6.8 (7)° out of the plane of the phenyl ring. In the crystal, the molecules are linked by N—H⋯N and N—H⋯O hydrogen bonds, forming sheets in the bc plane. In addition, a weak C—H⋯N interaction is observed.
“…For background to pyrazole-based ligands, see; Ahmed et al (2005); Abonia et al (2002Abonia et al ( , 2004Abonia et al ( , 2010; Guerrero et al (2009); Quiroga et al (2008); Schutznerová , et al (2012). For structure of an isomer of the title compound, see: Low et al (2004).…”
Section: Related Literaturementioning
confidence: 99%
“…As a part of our current research work focused on the development of new bioactive heterocyclic compounds and continuing with the use of pyrazolic Schiff bases (Quiroga et al, 2008;Abonia et al 2002Abonia et al , 2004Abonia et al , 2010, in the synthesis of pyrazolopyrimidines, we want to describe the compound 5-amino-3-tert-butyl-1-(3-nitro-phenyl)-1H-pyrazole (I), which is a structural isomer of a related compound previously reported by Low (Low et al, 2004).…”
In the title compound, C13H16N4O2, the pyrazole ring forms a dihedral angle of 50.61 (6)° with the 3-nitro-phenyl ring. The plane of the nitro group is twisted by 6.8 (7)° out of the plane of the phenyl ring. In the crystal, the molecules are linked by N—H⋯N and N—H⋯O hydrogen bonds, forming sheets in the bc plane. In addition, a weak C—H⋯N interaction is observed.
“…In methanolic solutions, compound 455 rearranges slowly to a thermodynamically more stable product, pyrazole derivative 456. 108 Subjected to a similar reaction with 1-vinyl-2-pyrrolidinone, 456 gives 3-t-butyl-1phenyl-6-(pyrrolidin-2-one-1-yl)-4,5,6,7-tetrahydro-1H-pyrazolo-[3,4-b]pyridine (462) in 50% yield. In this case, assistance of the amino group at C-5 that stabilizes initial cation 458 in a resonance form 459 is crucial for cleavage of the benzotriazolylÀCH 2 bond and further progress of the reaction (Scheme 94).…”
“…Use of alkynes instead of alkenes in the reaction depicted in Scheme 98 results in formation of 1,2-dihydroquinolines <1998JHC467> . Derivatives of aminoheterocycles, like compound 637 <2004T8839> also undergo readily [4+2] cyclocondensation with enol ethers and vinylamides. …”
Section: Reactivity Of Substituents Attached To Ring Nitrogensmentioning
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