Synthesis of Novel HIV‐1 Protease Inhibitors Based on Carbohydrate Scaffolds.

Abstract

Carbohydrates Carbohydrates U 0500 Synthesis of Novel HIV-1 Protease Inhibitors Based on Carbohydrate Scaffolds. -A number of title compounds like (I)-(III) are prepared. They show modest inhibitory activity for HIV-1 protease. -(MURPHY*, P. V.; O'BRIEN, J. L.; GOREY-FERET, L. J.; SMITH, A. B. I.; Tetrahedron 59 (2003) 13, 2259-2271; Dep. Chem., Univ. Coll., Belfield, Dublin 4, Ire.; Eng.) -Jannicke 29-156