Synthesis of novel chiral spiro-β-lactams from nitrile oxides and 6-(<i>Z</i>)-(benzoylmethylene)penicillanate: batch, microwave-induced and continuous flow methodologies

Alves, Américo J. S.; Silvestre, J.; Melo, Teresa M. V. D. Pinho e

doi:10.1039/d2ra04848e

RSC Adv.

2022

DOI: 10.1039/d2ra04848e

|View full text |Cite

Synthesis of novel chiral spiro-β-lactams from nitrile oxides and 6-(Z)-(benzoylmethylene)penicillanate: batch, microwave-induced and continuous flow methodologies

Américo J. S. Alves

J. Silvestre

Teresa M. V. D. Pinho e Melo

Abstract: The first examples of the diastereoselective 1,3-dipolar cycloaddition reaction of nitrile oxides and 6-alkylidene penicillanates leading to chiral spiroisoxazoline-penicillanates are reported.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2023

Publication Types

Select...

Book1

Relationship

Self Cite0

Independent1

Authors

Journals

Cited by 1 publication

References 67 publications

(36 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

Four-membered ring systems

Sánchez,

Anaya

2023

Progress in Heterocyclic Chemistry

View full text Add to dashboard Cite

Four-membered ring systems

Sánchez,

Anaya

2023

Progress in Heterocyclic Chemistry

View full text Add to dashboard Cite

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

hi@scite.ai

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Synthesis of novel chiral spiro-β-lactams from nitrile oxides and 6-(Z)-(benzoylmethylene)penicillanate: batch, microwave-induced and continuous flow methodologies

Abstract: The first examples of the diastereoselective 1,3-dipolar cycloaddition reaction of nitrile oxides and 6-alkylidene penicillanates leading to chiral spiroisoxazoline-penicillanates are reported.

Cited by 1 publication

References 67 publications

Four-membered ring systems

Four-membered ring systems

Contact Info

Product

Resources

About