Recent advancements in synthesizing Schiff bases, including sustainable and highly customizable approaches, are examined, offering insights into how their structures can be tailored for specific purposes. Schiff bases find applications in various fields, such as materials science, which contribute to developing polymers, metal-organic frameworks, nanocomposites, and medicinal chemistry, which serve as promising drug candidates. Additionally, they play crucial roles in coordination chemistry catalysis and have potential applications in emerging areas like nanotechnology and renewable energy, contributing to the development of nanomaterials and energy storage systems. This chapter provides a comprehensive overview of this synthesis and its applications, catering to researchers, students, and professionals looking to explore the multifaceted landscape of Schiff base compounds in contemporary organic chemistry.
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