Synthesis of novel 1,4-naphthoquinone derivatives: antibacterial and antifungal agents

On the investigation of hybrid quinones: synthesis, electrochemical studies and evaluation of trypanocidal activity

“…Finally, several reports have described chalcogen-containing quinones with antibacterial, antifungal 38 and antitumor activities, 39 and the last two decades have witnessed a growing interest in selenium-containing compounds with potential 'redox modulating' properties. Certain redox catalysts containing quinone-and chalcogen-bearing building blocks have shown considerable importance, with activity against cancer cells and other biological targets.…”

Synthesis and Characterization of Novel N-, S-, O-Substituted P-Chloranil Derivatives

“…Another application area for p-chloranil derivatives is acceptors in charge-transfer complexes. [8] A large number of chemical derivatives with 1,4-naphthoquinone [9,10] and benzoquinone [11] have been synthesized by our group before. As a continuation of the synthesis of interesting cyclic thio(crown)ether structures, herein we report novel intermolecular compounds with diquinone moiety.…”

Investigation of the antibacterial and antifungal activity of thiolated naphthoquinones

“…Compounds containing thiol have a broad spectrum of biological actions and have generated wide research interest. Some sulfide and sulfoxide quinones have been reported to have antifungal activity (De Paiva, Lima, Figueiredo, & Kaplan, 2004) and synthetic thiol containing derivatives of 1,4-naphthoquinone have been reported as potent antimicrobial and anticancer agents (Braud et al, 2008;Buchkevych, Stasevych, Chervetsova, Musyanovych, & Novikov, 2012;Ibis et al, 2013;Ibis et al, 2016;Tandon, Maurya, Verma, Kumar, & Shukla, 2010).…”