Synthesis of Nimesulide Nanoparticles in the Microemulsion Epikuron/Isopropyl Myristate/Water/n-Butanol (or Isopropanol)

Debuigne, F.; Cuisenaire, J.; Jeunieau, L.; Masereel, Bernard; Nagy, J.B.

doi:10.1006/jcis.2001.7879

Cited by 59 publications

(37 citation statements)

References 11 publications

(18 reference statements)

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“…It was proposed that whilst the energy of interactions between the droplets was negligible, the interfacial free energy could be zero or even negative if the interfacial tension lies between 10-2-10-13 mN/m (4). Instability then occurs due to the Ostwald ripening effect, with coalescence of particles leading to increase in the size of nanoparticles and thereby destabilization of the nanodroplets with subsequent sediment of particles (5,6).…”

Section: Introductionmentioning

confidence: 99%

Factors Affecting the Stability of Nanoemulsions—Use of Artificial Neural Networks

et al. 2009

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Section: Introductionmentioning

confidence: 99%

Factors Affecting the Stability of Nanoemulsions—Use of Artificial Neural Networks

et al. 2009

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“…The microemulsion synthesis route is a well established lab-scale method for the controlled production of narrowly distributed nanoparticles. Various materials like metals [2], polymers [3], metal oxides [4], borides [5], carbonates [6], silica [7], pharmaceuticals [8], semiconductors [9], and sulfate [10] have already been successfully produced by this technique.…”

Section: Introductionmentioning

confidence: 99%

Dynamic Process Model for Nanoparticle Precipitation in Microemulsion Systems

2008

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The controlled technical-scale production of nanoparticles is a very important aspect in nanotechnology. The synthesis of nanoparticles by microemulsion precipitation is a laboratory-scale technique which has to be scaled up to technical use. For a better understanding of this complex process, a numerically efficient process model was derived which is applicable to CFD studies, process control and the analysis of the scale-up behavior. The model contains microemulsion specific nucleation kinetics allowing for the discrete character of the system on a molecular scale, and growth kinetics adopted from bulk phase approaches. The major output of this process model is the computationally efficient and reliable determination of the mean particle diameter as a function of time. A comparison with experimentally obtained data from barium sulfate precipitation showed a qualitatively good agreement.

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“…The synergy between nanotechnology and the biological sciences is especially important in pushing the frontiers in medicine, [1][2][3] environment, 4 and food technology. 5 For biomedical sciences, especially, nanotechnology holds a lot of potential in areas such as drug delivery, gene delivery, and bioassays.…”

Section: Introductionmentioning

confidence: 99%

“…6,14 In this context, W/O's have been used in the preparation of silica, 6,15 titania, 11 perovskites, 16 semiconductor nanoparticles, 10,17,18 and even organic nanoparticles. 1 Consequently, SiO 2 nanoparticles prepared in W/O's have been reported to encapsulate a wide variety of luminescent compounds, ranging from semiconductor nanocrystals, 19,20 YF 3 nanoparticles, 9 organic/inorganic dyes, and lanthanide (Ln) chelates. 21,22 In this work, we have investigated this approach to encapsulate lanthanide chelates in silica nanoparticles prepared by the Stober method.…”

Section: Introductionmentioning

confidence: 99%

Nanoencapsulation of Luminescent 3-Hydroxypicolinate Lanthanide Complexes

et al. 2009

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We have synthesized luminescent nanoparticles comprising a core of lanthanide complexes and shells of amorphous silica using reverse micelles as nanoreactors. 3-Hydroxypicolinate complexes of Eu(III), Tb(III), and the corresponding heteronuclear complexes have been investigated as the photoactive cores. The size of the silica particles is within the nanometer scale, which, together with the ability for surface biofunctionalization, opens up perspectives for their use in bioapplications. Optical studies of the as-prepared nanoparticles reveal that the luminescence properties of the 3-hydroxypicolinate complexes in the matrices are markedly different from their original features.

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Synthesis of Nimesulide Nanoparticles in the Microemulsion Epikuron/Isopropyl Myristate/Water/n-Butanol (or Isopropanol)

Cited by 59 publications

References 11 publications

Factors Affecting the Stability of Nanoemulsions—Use of Artificial Neural Networks

Factors Affecting the Stability of Nanoemulsions—Use of Artificial Neural Networks

Dynamic Process Model for Nanoparticle Precipitation in Microemulsion Systems

Nanoencapsulation of Luminescent 3-Hydroxypicolinate Lanthanide Complexes

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