Synthesis of nickel-doped ceria nanospheres for in situ profiling of Warfarin sodium in biological media

Maheshwaran, Selvarasu; Akilarasan, Muthumariappan; Chen, Shen‐Ming; Tamilalagan, Elayappan; Keerthiga, Elayappan; Alothman, Asma A.; Alqahtani, Khadraa N.; Ganesh, P-S

doi:10.1016/j.bioelechem.2022.108166

Cited by 11 publications

(3 citation statements)

References 49 publications

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“…59 For example, cerium oxide electrode materials have exhibited outstanding electrocatalytic activity because of their mixed-valence oxidation state conversion between Ce( iii ) and Ce( iv ), which helped with fast electron transport. 94 Furthermore, Fe 3 O 4 electrode materials have unique properties such as high mobility of oxygen ions, superparamagnetic, low toxicity, biocompatibility, small sizes, and extraordinary catalytic activities in oxidative processes, which lead to increased sensitivity and stability of pesticide detection. 95,96 Spinel-type oxides demonstrate exceptional structural durability.…”

Section: Metal Oxidesmentioning

confidence: 99%

Metal oxide-based electrochemical sensors for pesticide detection in water and food samples: a review

Maheshwaran,

Chen,

Lin

et al. 2024

Environ. Sci.: Adv.

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Section: Metal Oxidesmentioning

confidence: 99%

Metal oxide-based electrochemical sensors for pesticide detection in water and food samples: a review

Maheshwaran,

Chen,

Lin

et al. 2024

Environ. Sci.: Adv.

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“…The increased electrochemical response for warfarin compared to unmodified glassy carbon electrodes was attributed to the increased active surface area after the modification. Similarly, a nickel-doped ceria nanosphere-modified glassy carbon electrode was employed to quantify warfarin [77]. The presence of nickel-doped ceria nanospheres showed excellent electrocatalytic capability for warfarin detection with a linear range of 10 nM to 151 µM and a detection limit of 6.3 nM.…”

Section: Electrochemical Sensors For Anticoagulants Using Modified El...mentioning

confidence: 99%

Electrochemical Monitoring in Anticoagulation Therapy

Mruthunjaya,

Torriero

2024

Molecules

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The process of blood coagulation, wherein circulating blood transforms into a clot in response to an internal or external injury, is a critical physiological mechanism. Monitoring this coagulation process is vital to ensure that blood clotting neither occurs too rapidly nor too slowly. Anticoagulants, a category of medications designed to prevent and treat blood clots, require meticulous monitoring to optimise dosage, enhance clinical outcomes, and minimise adverse effects. This review article delves into the various stages of blood coagulation, explores commonly used anticoagulants and their targets within the coagulation enzyme system, and emphasises the electrochemical methods employed in anticoagulant testing. Electrochemical sensors for anticoagulant monitoring are categorised into two types. The first type focuses on assays measuring thrombin activity via electrochemical techniques. The second type involves modified electrode surfaces that either directly measure the redox behaviours of anticoagulants or monitor the responses of standard redox probes in the presence of these drugs. This review comprehensively lists different electrode compositions and their detection and quantification limits. Additionally, it discusses the potential of employing a universal calibration plot to replace individual drug-specific calibrations. The presented insights are anticipated to significantly contribute to the sensor community’s efforts in this field.

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“…The increased electrochemical response for warfarin compared to unmodified glassy carbon electrodes was attributed to the increased active surface area after the modification. Similarly, a nickel-doped ceria nanospheresmodified glassy carbon electrode was employed to quantify warfarin [77]. The presence of nickeldoped ceria nanospheres showed an excellent electrocatalytic capability for warfarin detection with a linear range of 10 nM to 151 µM and a detection limit of 6.3 nM.…”

Section: Electrochemical Sensors For Anticoagulants Using Modified El...mentioning

confidence: 99%

Electrochemical Monitoring on Anticoagulation Therapy

Mruthunjaya,

Torriero

2024

Preprint

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The process of blood coagulation, wherein circulating blood transforms into a clot in response to internal or external injury, is a critical physiological mechanism. Monitoring this coagulation process is vital to ensure that blood clotting occurs neither too rapidly nor too slowly. Anticoagulants, a category of medications designed to prevent and treat blood clots, require meticulous monitoring to optimise dosage, enhance clinical outcomes, and minimise adverse effects. This review article delves into the various stages of blood coagulation, explores commonly used anticoagulants and their targets within the coagulation enzyme system, and emphasises the electrochemical methods employed in anticoagulant testing. Electrochemical sensors for anticoagulant monitoring are categorised into two types. The first type focuses on assays measuring thrombin activity via electrochemical techniques. The second type involves modified electrode surfaces that either directly measure the redox behaviour of anticoagulants or monitor the response of standard redox probes in the presence of these drugs. The review provides a comprehensive list of different electrode compositions and their detection and quantification limits. Additionally, it discusses the potential of employing a universal calibration plot to replace individual drug-specific calibrations. The insights presented are anticipated to significantly contribute to the sensor community's efforts in this field.

show abstract

Synthesis of nickel-doped ceria nanospheres for in situ profiling of Warfarin sodium in biological media

Cited by 11 publications

References 49 publications

Metal oxide-based electrochemical sensors for pesticide detection in water and food samples: a review

Metal oxide-based electrochemical sensors for pesticide detection in water and food samples: a review

Electrochemical Monitoring in Anticoagulation Therapy

Electrochemical Monitoring on Anticoagulation Therapy

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