2007
DOI: 10.3998/ark.5550190.0008.a25
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Synthesis of new substituted thieno[2,3-d]imidazolone from hydantoin

Abstract: Abstract1,3-Dibenzyl-5-chloro-2-oxo-4-imidazoldinecarbaldehyde 3 was prepared in two steps from hydantoin using Vilsmeier-Haack reagent. Treatment of 3 with sodium sulfide nonahydrate and different activated halides or methyl thioglycolate afforded new substituted thieno [2,3-d]imidazolones.

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“…The preparation of the key intermediate 108 in this reaction was accomplished via the Vilsmeier–Haack reaction of 1,3-dibenzyl-2,4-imidazolidinedione 107 (Scheme 34 ). 66 The 1,3-dibenzyl-2,4-imidazolidinedione 108 can then be transformed into thieno[2,3- d ]imidazolones 109 .…”
Section: Formylation and Chlorinationmentioning
confidence: 99%
“…The preparation of the key intermediate 108 in this reaction was accomplished via the Vilsmeier–Haack reaction of 1,3-dibenzyl-2,4-imidazolidinedione 107 (Scheme 34 ). 66 The 1,3-dibenzyl-2,4-imidazolidinedione 108 can then be transformed into thieno[2,3- d ]imidazolones 109 .…”
Section: Formylation and Chlorinationmentioning
confidence: 99%