Synthesis of New Methoxy Actived Mono and Bis-indole Compounds

Abstract

An indole hydrazone has successfully been synthesized employing Schiff base reaction conditions starting from 4,6-dimethoxy-2,3-diphenylindole-7-carbaldehyde with hydrazine hydrate. The reaction of this compound with acetone yielded indole based imine compound. The structure of targeted compound was identified by mass and 1H spectroscopy along with single crystal X-ray diffraction technique. Also, bromination of bis-indole with N-bromo succinimide was produced corresponding bromo bis-indol derivative.

Synthesis and Characterization of New Indole Based Benzothiazole

“…Such cyclic compounds can display a wide range of biological activities depending on the type of pharmacophore group they contain. It is well known that the construction of novel scaffolds possesses two or more types of heterocycles could afford a novel entity with increased biological activities [1][2][3]. Among the heterocyclic units, indole and benzothiazole derivatives are of significant synthetic interest because of their diverse range of biological activity.…”