Synthesis of New Fluorescent Derivatives of 1,7,10,16‐Tetraoxa‐4,13‐diazacyclooctadecane (Kryptofix K22).

Abstract

7,10,16-Tetraoxa-4,13-diazacyclooctadecane (Kryptofix K22). -The preparation of title compounds (III) starting from commercially available Kryptofix K22 (I), their spectral data, and evaluation of their hydrophobicity/hydrophilicity behavior are described. -(BEM*, M.; CAPROIU, M. T.; VASILESCO, M.; TUDOSE, M.; SOCOTEANU, R.; NICOLAE, A.; CONSTANTINESCU, T.; BANCIU, M. D.; Rev. Roum. Chim. 48 (2003) 9, 709-715; Inst. Phys. Chem., Rom. Acad., RO-77208 Bucharest, Rom.; Eng.) -M. Schroeter 22-173

4-(D-Glucosamino)-7-nitrobenzoxadiazole: synthesis, anomers, spectra, TLC behavior, and applications

“…[1][2][3][4][5][6][7][8] Moreover, some of these derivatives have antileukemic or immunosuppressive properties. 1,2,9 Glucosamine (2-amino-2-deoxy-D-glucose) (1) is one of the constituents of chitin, chitosan, and mucopolysaccharides and has important biomedical applications, including pharmaceutical preparations for treating cartilage diseases of joints.…”

Linear and cyclic ethylene-glycols labelled with nitrobenzofurazan motifs

“…Compounds A-C are known in literature, and they were obtained using the same procedure, with some slight changes. [10][11][12] Mainly, these compounds can be easily obtained by reacting NBD-chloride with the corresponding aza-or diaza-crown-ether, in the presence of a base. Compounds D-F were obtained in a similar way, starting from 1,8diamino-3,6-dioxaoctane, 4-aminobenzo-15crown-5-ether, and 4-aminobenzo-18-crown-6ether; the reactions work well in acetonitrile as a solvent and in the presence of sodium hydrogen carbonate as a base (see Experimental part for details).…”