Synthesis of new coumarin 3-(N-aryl) sulfonamides and their anticancer activity

Design, synthesis and evaluation of 2,4-diarylpyrano[3,2-c]chromen-5(4H)-one as a new class of non-purine xanthine oxidase inhibitors

“…The presence of coumarin architecture in naturally occurring phytoconstituents with anticancer 15,16 , anti-HIV 17 , antituberculosis 18 , anti-influenza 19 , antialzheimer 20,21 , anti-inflammatory 22 , antiviral 23 , antimicrobial 13 and xanthine oxidase inhibitory activities [24][25][26] makes it a privileged structure. Among the diverse array of biological activities possessed by coumarins, we are particularly interested towards their xanthine oxidase inhibitory potential which has also been extensively explored [24][25][26] .…”

In vitro inhibition effect of some coumarin compounds on purified human serum paraoxonase 1 (PON1)

“…The diverse biological activities of natural and synthetic coumarin derivatives as anticoagulants and antithrombotics are well known 15 . The biological effects observed include antibacterial, antithrombotic and vasodilatory, antimutagenic, lipoxygenase and cyclooxygenase inhibition, scavenging of reactive oxygen species and antitumourigenic effects 16 .…”

A one pot synthesis of fused chromenones

“…[1][2][3][4][5][6][7][8][9][10] Recently, the anticoagulant, antibacterial, antihelminthic, hypothermal and vasodilatory properties of chromene have been reviewed. 1 Fused chromenones are interesting due to their significant antibacterial [11][12][13][14][15] and novobiocin 16,17 activities.…”