Synthesis of New Chiral Monosulfonamides Prepared from (11R,12R)-11,12-Diamino-9,10-dihydro-9,10-ethanoanthracene and their Use as Ligands for Asymmetric Catalysis

Abstract

New chiral monosulfonamides <strong>…</strong>6-16 containing (11<em>R</em>,12<em>R</em>)-diamino-9,10-dihydro-9,10-ethanoanthracene as carbon skeleton were prepared. Compounds <strong>6-12</strong>, <strong>15</strong> and <strong>16</strong> were used as optically active ligands in the enantioselective ethylation of benzaldehyde. Moreover, the monosulfonamides <strong>6-10</strong> were tested in the asymmetric transfer hydrogenation (ATH) of acetophenone with Rh(Cp*)L* complex.