Synthesis of new benzo[a]phenoxazinium probes possessing carboxylic ester, hydroxyl and amino functional groups: Photophysical studies in dry ethanol and conjugation with CdTe quantum dots

Synthesis, photophysical characterisation and photostability studies of NIR probes with aliphatic, aromatic and chlorinated terminals in 5- and 9-amino positions of benzo[ a ]phenoxazines

“…In that basic form the π-conjugation system would not be significantly changed resulting in a less blue shifted absorption than when the deprotonation occurs at the 5-position. As in previous studies [15,17], compound 5 shows that double alkylation at 9-position results in red shift of the acid form absorption.…”

“…where C T is the compound total concentration, K a , is the dissociation constant and K EtOH is ethanol self-dissociation constant. This model was previously and successfully applied in compounds of the same family [17,28]. In Figure 2C it is shown that the fitting of the fraction of basic form, obtained from spectral deconvolution procedure, with eq.…”

“…Considering the importance and as a continuation of our current research interest towards the design, synthesis and application of NB derivatives with different substituents [15][16][17][18][19][20][21][22][23][24][25], the present work is focused in the preparation of a new set of benzo[a]phenoxazinium chlorides with aliphatic, aromatic and chlorinated terminals in 5-and 9-amino positions of the heteroaromatic system. The photophysical behaviour of these compounds in anhydrous ethanol and in aqueous solutions was investigated along with photostability studies in water and in biological medium.…”

<p>A Lysosome-Targetable Fluorescence Probe Based on L-Cysteine-Polyamine-Morpholine-Modified Quantum Dots for Imaging in Living Cells</p>

“…[47][48][49][50][51] Amino acid contain an amino and carboxyl group, therefore they can be directly linked to the surface of QDs and other drugs with the antitumor activity or targetable groups. [52][53][54][55][56][57] In this paper, we synthesized a new class of modified QDs with small size, good water solubility, disperse uniformly and strong optical emission properties. In such models, four types of amino acid-polyamine-morpholine derivatives were used and the bio-activities of modified QDs were greatly improved.…”

<strong>Benzo[</strong><em><strong>a</strong></em><strong>]phenoxazinium chlorides functionalized with chloride atoms and/or ester groups</strong>

“…As a continuation of the investigation of our research group, [6][7][8][9][10] in this proceeding we intend to…”