Synthesis of new antibacterial composite coating for titanium based on highly ordered nanoporous silica and silver nanoparticles

Massa, Miguel A.; Covarrubias, Cristian; Bittner, Mauricio; Fuentevilla, Ignacio Andrés; Capetillo, Pavel; Marttens, Alfredo von; Carvajal, Juan Carlos

doi:10.1016/j.msec.2014.08.057

Cited by 100 publications

(66 citation statements)

References 37 publications

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“…Both in vitro [38,39] and in vivo studies [40,41] reported a positive correlation between fibrin adhesion and surface wettability. Fibrin adhesion is influenced by different parameters: Blood drop extension, gravity of the drop, liquid characteristics, and thermodynamics aspects [42].…”

Section: Discussionmentioning

confidence: 98%

The Surface Anodization of Titanium Dental Implants Improves Blood Clot Formation Followed by Osseointegration

et al. 2018

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Abstract:The anodization of titanium dental implant influences the biologic processes of osseointegration. 34 grit-blasted and acid-etched titanium specimens were used to evaluate microand nano-roughness (R a ), contact angle (θ) and blood clot extension (bce). 17 samples were anodized (test) while the remaining were used as control. The bce, was measured using 10 µL of human blood left in contact with titanium for 5 min at room temperature. The micro-and nano-scale R a were measured under CLSM and AFM, respectively, while the θ was analyzed using the sessile drop technique. The bone-implant contact (BIC) rate was measured on two narrow implants retrieved for fracture. bce was 42.5 (±22) for test and 26.6% (±13)% for control group (p = 0.049). The micro-R a was 6.0 (±1.5) for the test and 5.8 (±1.8) µm for control group (p > 0.05). The θ was 98.5 • (±18.7 • ) for test and 103 • (±15.2 • ) for control group (p > 0.05). The nano-R a was 286 (±40) for the test and 226 (±40) nm for control group (p < 0.05). The BIC rate was 52.5 (±2.1) for test and 34.5% (±2.1%) for control implant (p = 0.014). (Conclusions) The titanium anodized surface significantly increases blood clot retention, significantly increases nano-roughness, and favors osseointegration. When placing dental implants in poor bone quality sites or with immediate loading protocol anodized Ti6Al4V dental implants should be preferred.

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Section: Discussionmentioning

confidence: 98%

The Surface Anodization of Titanium Dental Implants Improves Blood Clot Formation Followed by Osseointegration

et al. 2018

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“…Majority of them were generated by chemical, 18 sonochemical 19 or sol-gel based methods. 20 Juan et al deposited Ag NPs on titanium surface by salinization. Their results showed that the composite Ag-TiO 2 surface could kill 94% of Staphylococcus aureus and 95% of Escherichia coli after 24 hours incubation.…”

Section: Introductionmentioning

confidence: 99%

“…Korshed et al NP concentrations (10,20 and 50 µg/mL) or 10 µL dH 2 O as control and further incubated at 37°C overnight. Lysis buffer 10 µL from the LDH assay kit (Fisher Scientific, Loughborough, UK/Cat No 88954) was then added and mixed by gently tapping and incubated at 37°C for 45 minutes.…”

mentioning

confidence: 99%

Antibacterial mechanisms of a novel type picosecond laser-generated silver-titanium nanoparticles and their toxicity to human cells

Korshed¹,

Li²,

Li³

et al. 2017

IJN

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In this study, we explored the antibacterial mechanisms for a novel type of Ag-TiO 2 compound nanoparticles (NPs) produced from an Ag-TiO 2 alloy using a picosecond laser and evaluated the toxicity of the Ag-TiO 2 NPs to a range of human cell types. Transmission electron microscopy was used to determine the morphology, shapes, and size distribution of the laser-generated Ag-TiO 2 NPs. UV-visible spectrometer was used to confirm the shift of light absorbance of the NPs toward visible light wavelength. Results showed that the laser-generated Ag-TiO 2 NPs had significant antibacterial activities against both Gram-negative and Gram-positive bacterial strains, including Escherichia coli, Pseudomonas aeruginosa , and the methicillin-resistant Staphylococcus aureus . Increased level of reactive oxygen species was produced by E. coli after exposure to the Ag-TiO 2 NPs, which was accompanied with lipid peroxidation, glutathione depletion, disintegration of cell membrane and protein leakage, leading to the cell death. Five types of human cells originated from lung (A549), liver (HePG2), kidney (HEK293), endothelium cells (human coronary artery endothelial cells [hCAECs]), and skin (human dermal fibroblast cells [HDFc]) were used to evaluate the cytotoxicity of the laser-generated Ag-TiO 2 NPs. A weak but statistically significant decrease in cell proliferation was observed for hCAECs, A549 and HDFc cells when co-cultured with 2.5 µg/mL or 20 µg/mL of the laser-generated Ag-TiO 2 NPs for 48 hours. However, this effect was no longer apparent when a higher concentration of NPs (20 µg/mL) was used after 72 hours of co-culture with human cells, suggesting a possible adaptive process in the cells had occurred. We conclude that picosecond laser-generated Ag-TiO 2 NPs have a broad spectrum of antibacterial effect, including against the drug-resistant strain, with multiple underlying molecular mechanisms and low human cell toxicity. The antimicrobial properties of the new type of picoseconds laser-generated Ag-TiO 2 compound NPs could have potential biomedical applications.

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“…Typical examples of functional coatings are self-cleaning [5,6], easy-to clean (anti-graffiti) [7], antifouling [8], soft feel [9], antibacterial [10,11] and anti-corrosive [12,13] Nano-materials in Coatings industry:-Nano-particles are generally considered to be a number of atoms or molecules bonded together with radius of 100nm. A cluster of one nanometer radius has approximately 25 atoms, but most of them are on the surface of the cluster [14].…”

Section: Introduction:-mentioning

confidence: 99%

Influence of Nano Alpha Aluminum Oxide (Α -Al2o3) on Thermal Properties of Nano Insulation Coating.

Hashim¹,

Salih²,

Jameel.³

2016

IJAR

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Thermal insulation coatings are a class which begins to attract more focus and priority in recent researches because of their importance and their numerous applications in different civil and industrial fields. In this research, the effect of nano alpha aluminum oxide (α-Al 2 O 3 ) on the thermal insulation of polymer based paint was investigated. The different weight fractions of nano aluminum oxide ( 2%, 3%,4% and 5% wt. of polymer weight) were added to the formulation which contained nano titanium dioxide and nano calcium carbonate and poly vinyl acetate polymer solution . Dip coating technique was used to coat all samples. The highest increase in insulation value (R-value) was recorded for 4 %wt. sample where its improvement percentage reached to 24.42% compared with the sample which was contained no nano aluminum oxide addition while the other samples showed varied values. The microscopic images showed that 4% sample has well dispersed than others. The Knudsen diffusion effect is the proposed mechanism explaining the insulation improvement.Copy Right, IJAR, 2016,. All rights reserved.

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Synthesis of new antibacterial composite coating for titanium based on highly ordered nanoporous silica and silver nanoparticles

Cited by 100 publications

References 37 publications

The Surface Anodization of Titanium Dental Implants Improves Blood Clot Formation Followed by Osseointegration

The Surface Anodization of Titanium Dental Implants Improves Blood Clot Formation Followed by Osseointegration

Antibacterial mechanisms of a novel type picosecond laser-generated silver-titanium nanoparticles and their toxicity to human cells

Influence of Nano Alpha Aluminum Oxide (Α -Al2o3) on Thermal Properties of Nano Insulation Coating.

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