Synthesis of New 3-(2-Chloroquinolin-3-yl)-5-Phenylisoxazole Derivatives via Click-Chemistry Approach

Ultrasound-promoted synthesis of novel N-arylamino-3,5′-biquinoline derivatives: their applications in live-cell imaging and in vitro anticancer activity evaluation

“…IR (KBr) (n max , cm À1 ): 3440, 3336, 3225, 2220, 1642, 1566, 1490, 1420, 1073, 1004, 837, 824, 803 cm À1 . 1 H NMR (300.13 MHz, DMSO-d 6 ): 2.51 (3H, s, CH 3 ), 6.85 (1H, dd, 3 13 +4 , 19), 682 (M +3 , 21), 681 (M +2 , 88), 680 (M +1 , 80), 679 (M + , 100), 677 (25), 676 (50), 645 (18), 644 (33), 600 (4), 563 (14), 522 (6), 482 (5), 281 (5), 260 (13), 228 (17), 207 (6), 148 (51), 83 (15), 56 (61), 55 (51), 50 (8) 2 0 -Amino-4 0 ,7 0 -bis(4-bromophenyl)-2-chloro-6-methoxy-[3,5 0biquinoline]-3 0 ,8 0 -dicarbonitrile (3d). Light yellow solid, m.p.…”

Synthesis, SAR studies, and insecticidal activities of certain N-heterocycles derived from 3-((2-chloroquinolin-3-yl)methylene)-5-phenylfuran-2(3H)-one against Culex pipiens L. larvae

“…The quinoline skeleton has been utilized for certain important engineered agrochemicals and to plan manufactured mixtures possessing many pharmacological effects. [21][22][23][24][25][26][27][28] Mosquitoes are the main vector of serious diseases that threaten human health and cause adverse socioeconomic impacts, particularly in subtropical and tropical climates. 29,30 Culex pipiens Linnaeus (Diptera: Culicidae) is a widely distributed and epidemic mosquito found in Egypt.…”

“…The quinoline skeleton has been utilized for certain important engineered agrochemicals and to plan manufactured mixtures possessing many pharmacological effects. 21–28…”

Molecular modeling and nonlinear optical properties of new isostructural halogenated dihydroquinolinones

“…1,2 Quinolinone or quinolone complexes (first synthesized in 1962 from chloroquine) are a class of synthetic compounds widely used in the development of new drugs with different substituents at the core of their structure. Some compounds with quinolinones in their skeleton are already used as drugs, 3 such as antitumor, 4 anticancer, 5 antibacterial, antifungal, 6 and anti-inflammatory. 7 Crystal engineering principles allow the transformation from conventional synthetic routes 8,9 to cocrystallization, resulting in the production of multicomponent solids with good practical application.…”