Synthesis of [n]‐ and [n.n]Cyclophanes by Using Suzuki—Miyaura Coupling.

Abstract

CyclophanesCyclophanes O 0450 Synthesis of [n]-and [n.n]Cyclophanes by Using Suzuki-Miyaura Coupling. -A number of novel cyclophanes are prepared. -(SMITH, B. B.; HILL, D. E.; CROPP, T. A.; WALSH, R. D.; CARTRETTE, D.; HIPPS, S.; SHACHTER, A. M.; PENNINGTON, W. T.; KWOCHKA*, W. R.; J. Org. Chem. 67 (2002) 15, 5333-5337; Dep. Chem., Western Carolina Univ., Cullowhee, NC 28723, USA; Eng.) -Jannicke 03-056

Indane-1,3-Dione: From Synthetic Strategies to Applications

“…Among the main methods reported in the literature, Wurtz coupling, [127] carbene insertion [128,129], Ni-catalyzed Grignard coupling [130], polymerization of p-xylene [131], pyrolysis of sulfones [132] or acyloin condensation [133] can be cited as popular reactions. Conversely, Suzuki-Miyaura cross-coupling reaction [134][135][136][137] or ring-closing metathesis [138][139][140][141][142][143][144][145][146][147] have been less studied. In 2012, a combination of these two key reactions (Suzuki-Miyaura cross-coupling reaction and ring-closing metathesis) has been conceived as a concise and efficient synthetic route to access to [4,4]-cyclophane derivatives [148].…”