Synthesis of monodisperse functional polymeric microspheres for immunoassay

Prokopov, N. I.; Gritskova, I. A.; Cherkasov, V. R.; Чалых, А. Е.

doi:10.1070/rc1996v065n02abeh000205

Cited by 53 publications

(16 citation statements)

References 154 publications

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“…4 behaved a peak at 610 nm attributing to the emission maximum of the precursor CdS nanoparticles, while such a peak was absent for the emission spectrum of the silica particles only (data not shown here). The photoluminescence from these core-shell CdS/SiO 2 QDs was consistent with that of the afforded CdS nanoparticles in the literature [24] . These results also demonstrated that the silica layer effectively encapsulated over the CdS QDs, which permitted the possibility for further modification and polymerization.…”

Section: Scheme 1 Synthesis Of Fluorescent Cds/sio 2 /Polymer Tri-laysupporting

confidence: 85%

“…Highly luminescent and stable CdTe QDs in sol-gel derived composite silica spheres coated with 5,11,17,23-tetra-tert-butyl-25,27-diethoxy-26,28-dihydroxycalix [4] arene (C[4]SiO 2 /CdTe) were prepared via a sol-gel technique in aqueous media and used as a selective fluorescent probe for the determination of pesticides [19] . Microspheres with functional groups have many applications in various fields, such as carriers for the immobilization of biological substances including enzymes, antibodies, etc [24] . To date, work has been reported on the utilization of microspheres as microscopic markers for antigens or antibodies on the surface cell [25] .…”

Section: Introductionmentioning

confidence: 99%

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Synthesis of CdS/SiO2/polymer tri-layer fluorescent nanospheres with functional polymer shells

et al. 2012

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Tri-layer CdS/SiO 2 /polymer hybrid nanospheres were synthesized by distillation precipitation polymerization of either ethyleneglycol dimethacrylate (EGDMA) or EGDMA together with comonomers having different functional groups, such as methacrylic acid, 4-vinylpyridine and 2-hydroxyethylmethacrylate, in the presence of 3-(methacryloxy)propyl trimethoxysilane (MPS)-modified CdS/SiO 2 nanoparticles as seeds in acetonitrile with 2,2′-azobisisobutyronitrile (AIBN) as initiator. In this approach, MPS-modified inorganic seeds were prepared by the modification of CdS/SiO 2 nanoparticles via the self-condensation reaction between the hydroxyl groups of sinaols, in which the CdS/SiO 2 nanoparticles were afforded by a reverse microemulsion technique for the synthesis of CdS core nanoparticles with the subsequent coating of silica layer. The polymer shell-layers encapsulated over the MPS-modified CdS/SiO 2 inorganic seeds via the efficient capture of the monomers and oligomers from the solution with the aid of the vinyl groups incorporated by the MPS modification, in which the polymer shell-thickness and functional groups including carboxyl, pyridyl and hydroxyl, were facilely controlled by the feed of EGDMA as well as the types of comonomers used for the polymerization. These nanospheres were characterized by transmission electron microscopy (TEM), Fourier-transform infrared spectroscopy (FT-IR), thermogravimetric analysis (TGA), fluorescence spectroscopy and zeta potential.

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Section: Scheme 1 Synthesis Of Fluorescent Cds/sio 2 /Polymer Tri-laysupporting

confidence: 85%

Section: Introductionmentioning

confidence: 99%

Synthesis of CdS/SiO2/polymer tri-layer fluorescent nanospheres with functional polymer shells

et al. 2012

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“…Moreover, the microspheres with carbonyl, hydroxyl, or amino groups can be used to immobilize antibodies and other proteins through covalently bonding [1,2]. However, numerous production and wide applications of synthesized polymer packing have led to environment problems due to the non-biodegradability of these materials.…”

Section: Introductionmentioning

confidence: 99%

Creation of regenerated cellulose microspheres with diameter ranging from micron to millimeter for chromatography applications

Luo

Zhang

2010

Journal of Chromatography A

102

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“…[1][2][3][4][5][6][7] The synthesis of polymer microspheres with carbonyl, hydroxyl and amino groups on their surfaces has been attempted using various methods, in which the functional groups have been used to covalently bind antibodies and other proteins to the microspheres. [8,9] The preparation of mercapto-containing polymers has been of significant interest due to their primary importance in biological systems [10] and their wide applications as stabilizers for gold nanoparticles of the mercapto functionality. [11] Mercapto-containing polymers can be prepared either by reduction of the disulfide groups [12] or by a reaction between the halogen atom and the sulfur containing nucleophilic precursor.…”

Section: Introductionmentioning

confidence: 99%

Synthesis of Monodisperse Polymer Microspheres with Mercapto Groups and Their Application as a Stabilizer for Gold Metallic Colloid

Yang

Huang

2005

Macro Chemistry & Physics

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Summary: Monodisperse polymer microspheres with functional mercapto groups on the surface were prepared from poly[(ethylene glycol dimethacrylate)‐co‐(2‐hydroxyethyl methacrylate)], poly(EGDMA‐co‐HEMA), microspheres successively through esterification of the active hydroxyl groups with acryloyl chloride to introduce carbon‐carbon double bonds and then the addition reaction of hydrogen sulfide to the double bond at pH 10–11. All of the polymer microspheres were characterized by scanning electron microscopy (SEM) and FT‐IR spectra. The mercapto‐functionalized polymer microspheres were utilized as a stabilizer for gold metallic colloids through coordination of the mercapto group on the polymer with gold metallic nanoparticles, which were prepared by the reduction of gold chloride trihydrate with sodium borohydride as the reductant. The size and morphology of the gold on the microspheres were determined to be of narrow dispersity (in the range 4–8 nm) by transmission electron microscopy (TEM).Preparation of mercapto‐modified polymer microspheres and their application as a stabilizer for gold metallic colloids.magnified imagePreparation of mercapto‐modified polymer microspheres and their application as a stabilizer for gold metallic colloids.

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Synthesis of monodisperse functional polymeric microspheres for immunoassay

Cited by 53 publications

References 154 publications

Synthesis of CdS/SiO2/polymer tri-layer fluorescent nanospheres with functional polymer shells

Synthesis of CdS/SiO2/polymer tri-layer fluorescent nanospheres with functional polymer shells

Creation of regenerated cellulose microspheres with diameter ranging from micron to millimeter for chromatography applications

Synthesis of Monodisperse Polymer Microspheres with Mercapto Groups and Their Application as a Stabilizer for Gold Metallic Colloid

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